Demo

Sr. Manager, Bioinformatics Operations (Hybrid) - West

Quest Diagnostics
San Juan Capistrano, CA Full Time
POSTED ON 1/1/2026
AVAILABLE BEFORE 1/30/2026
Job Description

Pay Range: $140,000.00 - $170,000.00 / year

Salary offers are based on a wide range of factors including relevant skills, training, experience, education, and, where applicable, certifications obtained. Market and organizational factors are also considered. Successful candidates may be eligible to receive annual performance bonus compensation.

Benefits Information

We are proud to offer best-in-class benefits and programs to support employees and their families in living healthy, happy lives. Our pay and benefit plans have been designed to promote employee health in all respects – physical, financial, and developmental. Depending on whether it is a part-time or full-time position, some of the benefits offered may include:

  • Day 1 Medical, supplemental health, dental & vision for FT employees who work 30 hours
  • Best-in-class well-being programs
  • Annual, no-cost health assessment program Blueprint for Wellness®
  • healthyMINDS mental health program
  • Vacation and Health/Flex Time
  • 6 Holidays plus 1 "MyDay" off
  • FinFit financial coaching and services
  • 401(k) pre-tax and/or Roth IRA with company match up to 5% after 12 months of service
  • Employee stock purchase plan
  • Life and disability insurance, plus buy-up option
  • Flexible Spending Accounts
  • Annual incentive plans
  • Matching gifts program
  • Education assistance through MyQuest for Education
  • Career advancement opportunities
  • and so much more!

As the Regional Manager of the Bioinformatics Operations (Applications) team, you will lead the west region directly contributing to our focus of delivering actionable diagnostic insights that enable superior patient care. The focus of this role is to oversee and deliver high quality, stable and efficient Bioinformatics Applications in our genetic laboratories. You will work in an agile environment, foster innovation and lead the team in validating, supporting, and extending fully automated clinical-grade bioinformatics applications that meet the needs of our customers. This role partners closely with business stakeholders, Product Owners, Bioinformatics Research Engineers, Laboratory/Medical Scientists, and Enterprise IT etc. You will ensure the appropriate service levels and sample TATs are maintained. In collaboration with stakeholders, this leader will define and implement the vision, strategy, and roadmap for quality products across the region both on prem and in the cloud.

This professional will work out of San Juan Capistrano, CA in a hybrid capacity (3 days onsite)

Responsibilities

Manage a team of bioinformaticians and drive accountability in order to support clinical genomics operations.

Efficiently manage the daily bioinformatics support needs, meeting business SLAs and TAT targets.

Work closely with the laboratory operations team to support samples moving through production.

Manage incidents through timely and effective communication, collaboration, escalation and expeditious resolution of issues.

Define and improve on-call schedules for incident response.

Creatively organize, build, and schedule a team of employees to provide full operational coverage across the region.

Maintain logs, audit trails, and health monitoring dashboards for operational resilience.

Monitor daily operational performance metrics and proactively address bottlenecks.

Manage the systems associated with Bioinformatics Operations that support the production samples on premises and in the cloud.

Familiarize and use the electronic document management systems, as needed for appropriate compliance documentation need.

Leverage planning and software development tools like Atlassian JIRA and Confluence, Smartsheets, etc, to effectively document, communicate and align with the teams.

Drive configuration, adoption and efficient usage of ticketing tools like ServiceNow.

Ensure raw and processed data integrity, retention and secure archival in line with Quest policies. Collaborate with respective IT teams as needed.

Work with Data Governance teams to maintain metadata accuracy and controlled access.

Lead and manage validation, quality control, documentation, automation, and support cross functional bioinformatics projects.

Collaborate with bioinformatics research and engineering teams on software version upgrades, tech. transfer, and product launches.

Work with engineering teams to maximize the quality and safety of our product offerings by expanding our existing CI/CD pipelines and layering them with data-driven process controls for daily product integrity checks.

Support our culture of continuous improvement with a will to win. Continuously work to employ agile methodology principles and improve best practices in software development, software deployment, process documentation with application and workflow version controls, and automated testing that satisfies, at minimum, requirements from accreditation/regulatory bodies such as CAP, CLIA, ISO and the FDA.

Engage and synchronize efforts with other regional managers across the US and the EU.

Implement a framework for competency training, mentoring the team and assessment across the support staff.

Evaluate the talent level of employees, annual goal setting, and drive actions to develop employee talent and address performance issues.

Identify and provide training and career growth opportunities for team members, with focus on upskilling.

People Leadership Responsibilities: Team of technical resources 5-7 full-time employees and contractors.

Qualifications

Required:

At least 7 years of software engineering experience or related.

A solid background in bioinformatics engineering, software development, technologies, standards, etc.

Strong understanding of software best practices and agile methodology to serve as role model for the team and maintain a high level of quality and scalability on the technical as well as scientific side.

Experience with building highly automated and optimized bioinformatics solutions applicable to AWS cloud and on-prem computing environments.

Proven success in changing leadership and creating engaged and inspired teams.

Influences and communicates effectively with non-technical audiences including senior business executives and managers.

Demonstrated leadership skills, project management skills, strong written and verbal skills, and organizational skills. Proven ability to drive process with indirect authority to project team members.

A sharp thinker who quickly grasps the technical implications of business processes, and able to provide valuable insight into the perspectives of users, managers, developers, and other stakeholders.

Comfortably moves between highly varying levels of abstraction from business strategy to IT strategy to high-level technical design.

Team player mindset and ability to work in an interdisciplinary team.

Goal-oriented, self-motivated, and driven to make a positive impact in healthcare.

Preferred

Experience with bioinformatics best practices, genomics, and healthcare.

Experience with building or managing LIMS, variant interpretation platforms and other such bioinformatic systems.

Experience with sensitive patient data (HIPAA regulations) and working in regulatory environments eg CLIA, CAP, FDA.

Experience working with multi-cultural, international teams.

Competencies

  • Workflow automation and orchestration
  • Scripting
  • Version control (Git), CI/CD practices
  • Data security and compliance awareness
  • Team leadership
  • Project management (Time management, organizing, planning)
  • Strong interpersonal skills with ability to develop, maintain effective relationships
  • Drive for results
  • Excellent problem solving and critical thinking
  • Collaboration skills

Education

B.S. in Computer Science, Software Engineering, or a related field. (Required)

Certifications

MSc/PhD degree in Computer Science, Software Engineering, Bioinformatics (Preferred)

Agile Certification (Preferred)

ABOUT THE TEAM

Quest Diagnostics honors our service members and encourages veterans to apply.

While we appreciate and value our staffing partners, we do not accept unsolicited resumes from agencies. Quest will not be responsible for paying agency fees for any individual as to whom an agency has sent an unsolicited resume.

Equal Opportunity Employer: Race/Color/Sex/Sexual Orientation/Gender Identity/Religion/National Origin/Disability/Vets or any other legally protected status.

Salary : $140,000 - $170,000

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