Demo

Senior DevOps Engineer

Proscia
Philadelphia, PA Full Time
POSTED ON 12/13/2025
AVAILABLE BEFORE 2/13/2026

About Proscia

Pathology is at the center of medicine and is undergoing a profound transformation as the final frontier of digitization in healthcare. We started Proscia to accelerate pathology’s transition from microscope to images—and to use AI to change the way we think about cancer.


We can’t change medicine alone. That’s why we’re looking for curious thinkers, big dreamers, developers, evangelists, pathologists, and scientists— exceptional talent to help us harness the great power of AI for good and advance humankind.


At Proscia, we push the limits of medicine and technology, solving problems the world has never solved before. We build software used by thousands of scientists and pathologists working on the front lines of fighting big enemies like cancer for patients around the globe. To accelerate our vision, Proscia has raised over $100M in capital from world-class healthcare and technology investors.

 

About the role


As a Senior DevOps Engineer, you’ll be a key contributor to Proscia’s platform—helping build the infrastructure that enables pathologists to diagnose patients more accurately and efficiently. Our product powers high-resolution virtual microscopy and AI-assisted workflows at massive scale. If you enjoy solving hard reliability and performance problems in data-intensive systems, this role will challenge you and offer uncommon growth opportunities.


You’ll work closely with engineering and technical operations teams to ensure our infrastructure, CI/CD pipelines, and observability stack support high-performance, compute-heavy workloads. You’ll also serve as a bridge between development and operations, helping teams ship quickly without compromising reliability or security.

Key Responsibilities:


  • Serve as the embedded operations advocate within engineering teams building applications for digital pathology and AI workflows.
  • Design, deploy, and maintain Kubernetes-based container orchestration platforms using Helm, ensuring scalability for large datasets and compute-intensive services.
  • Develop and maintain CI/CD pipelines (GitHub Actions) that support rapid iteration, testing, and safe production releases.
  • Optimize infrastructure for storage, transfer, and processing of very large files and high-throughput AI workloads.
  • Expand application observability through metrics and traces (OpenTelemetry/DataDog), and strengthen logging and alerting practices.
  • Use Infrastructure-as-Code (Terraform) to provision and evolve required cloud resources alongside engineering teams.
  • Partner with developers to streamline deployment of AI models and data pipelines into production.
  • Manage artifacts in private repositories to ensure secure, reliable distribution across environments.
  • Improve resiliency, recovery workflows, and operational readiness across services.
  • Collaborate with cross-functional partners to balance competing priorities in a fast-moving, innovation-driven environment.


Required Qualifications:


  • Deep expertise with Kubernetes, including Helm chart development and lifecycle management.
  • Strong containerization experience, including Docker and Docker Compose.
  • Proficiency with Terraform (or comparable IaC tooling) for production infrastructure.
  • Hands-on experience operating workloads on AWS and/or Azure.
  • Proven CI/CD ownership and implementation experience, ideally with GitHub Actions.
  • Strong background in observability tooling such as OpenTelemetry, DataDog, Prometheus, Grafana, or equivalents.
  • Experience supporting large-scale data pipelines and storage systems—especially for large image files or compute-heavy workloads.
  • Working knowledge of private artifact repositories (e.g., AWS CodeArtifact, Artifactory, GitHub Packages).
  • Excellent problem-solving skills, good judgment under pressure, and the ability to prioritize effectively in dynamic environments.


Preferred / Nice-to-Have Qualifications


  • Experience with distributed file systems or high-throughput storage solutions.
  • Familiarity with production AI/ML deployment patterns (model serving, data versioning, pipeline orchestration).
  • Knowledge of database performance tuning for large datasets.
  • Experience in industries with similar large-scale imaging or data-intensive workflows.
  • Exposure to regulated medical-device or other compliance-heavy development processes.


Beyond Just Work

As a company in healthcare, we want our people to be happy and healthy, in and out of the office. In addition to competitive pay, we ensure everyone on our team is supported with savings, schedule, and insurance options that promote long-term health and personal growth.


Our office environment is designed for creativity and agility: with walls as notepads and couches for collaboration. We’re located in the heart of Philadelphia, with views of the city so you can spend your time focusing on what matters most.


At Proscia, we don’t just accept differences—we celebrate them, we support them, and we thrive on them for the benefit of our employees, our products, and our community. Proscia is proud to be an equal opportunity workplace.

Salary.com Estimation for Senior DevOps Engineer in Philadelphia, PA
$114,757 to $143,108
If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Senior DevOps Engineer?

Sign up to receive alerts about other jobs on the Senior DevOps Engineer career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$117,024 - $149,811
Income Estimation: 
$137,568 - $176,908
Income Estimation: 
$92,369 - $122,605
Income Estimation: 
$117,024 - $149,811
Income Estimation: 
$117,024 - $149,811
Income Estimation: 
$137,568 - $176,908
Income Estimation: 
$137,568 - $176,908
Income Estimation: 
$158,960 - $205,707
Income Estimation: 
$71,493 - $96,419
Income Estimation: 
$92,369 - $122,605
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at Proscia

  • Proscia Philadelphia, PA
  • This position is on-site 2-3 days in Philadelphia About Proscia Pathology is at the center of medicine and is undergoing a profound transformation as the f... more
  • 6 Days Ago

  • Proscia Philadelphia, PA
  • About Proscia Pathology is at the center of medicine and is undergoing a profound transformation as the final frontier of digitization in healthcare. We st... more
  • 7 Days Ago

  • Proscia Philadelphia, PA
  • About Proscia Pathology is at the center of medicine, and is undergoing a profound transformation as the final frontier of digitization in healthcare. We s... more
  • Just Posted

  • Proscia Philadelphia, PA
  • About Proscia Proscia is revolutionizing pathology, the last major frontier in healthcare to embrace digital. As a leader in pathology AI software, we are ... more
  • 1 Day Ago


Not the job you're looking for? Here are some other Senior DevOps Engineer jobs in the Philadelphia, PA area that may be a better fit.

  • Nuuly Philadelphia, PA
  • Role Summary Nuuly is seeking a Senior DevOps Engineer to join our growing Platform Engineering team. In this role, you’ll be instrumental in building, sca... more
  • 9 Months Ago

  • Envestnet Berwyn, PA
  • Description Envestnet is seeking a Senior DevOps Engineer to join our Technology team. This is a hybrid role, with in-office work required at our Berwyn, P... more
  • 9 Days Ago

AI Assistant is available now!

Feel free to start your new journey!