What are the responsibilities and job description for the Manager, NGS Lab position at Predicine, Inc?
Job Summary:
Predicine is seeking an experienced Lab Manager / Senior Manager, NGS Laboratory Operations to lead day-to-day wet laboratory operations and support the continued growth of our NGS programs. This role manages laboratory personnel, workflows, scheduling, quality, productivity, and operational performance across multiple NGS assays and projects. The ideal candidate combines strong NGS technical expertise, people leadership, and operational management skills to ensure high-quality, efficient, and timely laboratory execution — from sample accessioning and library preparation through sequencing and QC — while partnering cross-functionally with Quality, R&D, Bioinformatics, Clinical/Project Management, and Supply Chain to keep laboratory operations scalable, compliant, and audit-ready.
Key Responsibilities & Time Allocation
Education
MinimumPreferredLevelBachelor's degreeMaster's degree or PhDField of StudyMolecular Biology, Genetics, Biochemistry, Biotechnology, Medical Laboratory Science, or a related fieldSame fields
Experience
MinimumPreferredWork Experience5 years of relevant molecular biology/NGS laboratory experience (additional experience expected for the Senior Manager level); demonstrated laboratory leadership or people-management experienceExperience in a CLIA/CAP-regulated molecular diagnostics or NGS laboratory
Required Skills & Qualifications
- Strong knowledge of NGS workflows, including nucleic acid extraction, library preparation, sequencing, and QC
- Experience managing laboratory workflow, staffing, priorities, and turnaround time in a production, clinical, diagnostic, CRO, or high-throughput laboratory environment
- Strong troubleshooting, organizational, communication, and problem-solving skills
- Ability to work effectively in a fast-paced environment with multiple concurrent projects
Preferred Skills & Qualifications
- Experience with liquid biopsy, plasma/cfDNA, tissue/FFPE, RNA, MRD, WES/WGS, or oncology NGS workflows
- Experience with Illumina NovaSeq X/X Plus or other high-throughput sequencing platforms
- Experience with laboratory automation, liquid handlers, and LIMS/BioLIMS
- Experience with assay validation, technology transfer, CAPA, audits, and regulatory inspections
- Demonstrated experience scaling laboratory operations and improving workflow efficiency
Additional Notes
- The position may be filled at either the Lab Manager or Senior Manager level, depending on the candidate's experience, technical expertise, leadership scope, and demonstrated ability to manage complex NGS laboratory operations
- This is primarily an onsite laboratory leadership position and may require schedule flexibility to support operational needs
Join Us
At Predicine, you won't just manage a lab — you'll lead the operational engine behind cancer diagnostics that clinicians and patients depend on. If you're a hands-on leader who thrives on building high-performing teams, driving operational excellence, and ensuring every sample tells an accurate story, we want to hear from you.
Apply today and help us turn breakthrough science into better patient outcomes.
Predicine is an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.