Demo

Program Executive, Drug Development and Commercial

Praxis Precision Medicines, Inc.
Boston, MA Full Time
POSTED ON 5/13/2026
AVAILABLE BEFORE 11/8/2026
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.

The Opportunity

Praxis is looking for a talented and experienced leader for a key program expected to advance best in class or first-in-class products for areas of high unmet medical need. The ideal candidate is a strong, multi-faceted leader who thrives in environments with high ambiguity, limited hierarchy, and real ownership of outcomes as the program continues its rapid trajectory of transformational patient impact.

This results-oriented individual will be characterized by a strong strategic mind, a collaborative nature and intellectual curiosity, and will credibly and enthusiastically work across the spectrum of research, development, technical operations, and commercialization. They will lead a cross-functional program team and be responsible and accountable for Praxis’ program strategy, driving decision-making, and ensuring efficient and high-quality execution.

Praxis is committed to a high-energy, fast-pace and flat organization where individuals work as peers with singular objective to bring drugs to patients. This role is not about coordinating consensus; it is about building alignment, deeply understanding all aspects of the development activities for the product and driving the program forward. The Program Lead must embrace and exemplify this way of working.

Primary Responsibilities

  • Internally and externally communicate a shared and bold vision for the program.
  • Lead, manage, and maintain the Program Team, partnering with functional leads to ensure team effectiveness and operational excellence while retaining clear accountability for program-level decisions.
  • Lead the creation and execution of the program strategy and integrated development plan(s).
  • In collaboration with the Program Team, define and deliver against program OKRs.
  • Provide strategic oversight for program budgets and resourcing, actively shaping—not just tracking—investment decisions.
  • Architect scenarios to inform decision making and program planning; ensure that the right skills and capabilities exist on the team to effectively execute on the program plan.
  • Be a role model for Praxons: inspire ambitious goals, give and receive direct feedback, and build trust through transparency and follow-through.
  • “Roll up sleeves and get hands dirty” for the benefit of the team and the program; wear multiple hats, step into gaps, and hold yourself to the same standards as the team.
  • Serve as the primary integration point with corporate processes without creating unnecessary bureaucracy.

Qualifications And Key Success Factors

  • Demonstrated drug development experience with a strong track record of cross-functional leadership; experience across the full development lifecycle strongly preferred
  • Strong holistic understanding of the drug development process across functions
  • Ability to translate strategy into execution, driving decisions that create value under real-world constraints
  • Clear, compelling communicator across internal and external stakeholders

What Sets Successful Praxons Apart

  • Comfort operating with limited hierarchy and high personal accountability
  • Learning agility and intellectual curiosity; ability to rapidly develop deep understanding of new therapeutic areas
  • Willingness to challenge assumptions, surface risks early, and engage in healthy debate in service of the best outcome
  • Demonstrated ability to balance urgency with rigor in fast-moving environments

The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.

Compensation & Benefits

At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together!

To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. Final salary range may be modified commensurate with job level, education, and experience.

Annualized Base Salary: $285,000 USD - $325,000 USD

Company Overview

Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members.

Diversity, Equity & Inclusion

Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws.

Attention: Job Scam Alert

Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to careers@praxismedicines.com.

Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.

Salary : $285,000 - $325,000

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Program Executive, Drug Development and Commercial?

Sign up to receive alerts about other jobs on the Program Executive, Drug Development and Commercial career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$73,522 - $95,253
Income Estimation: 
$65,352 - $83,351
Income Estimation: 
$79,703 - $117,266
Income Estimation: 
$70,882 - $94,516
Income Estimation: 
$89,191 - $127,928
Income Estimation: 
$76,615 - $106,090
Income Estimation: 
$115,491 - $158,336
Income Estimation: 
$102,413 - $133,130
Income Estimation: 
$109,705 - $144,044
Income Estimation: 
$119,541 - $162,386
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at Praxis Precision Medicines, Inc.

  • Praxis Precision Medicines, Inc. Boston, MA
  • Location: This position may be performed remotely but requires flexibility and willingness to travel as needed. Position Summary We’re looking for a dynami... more
  • 4 Days Ago

  • Praxis Precision Medicines, Inc. Boston, MA
  • The Opportunity As part of our Praxis Finance team, this role presents an opportunity to oversee the entire Accounting function. You will be responsible fo... more
  • 9 Days Ago

  • Praxis Precision Medicines, Inc. Boston, MA
  • The Opportunity: We are seeking highly engaged individuals to represent Praxis Precision Medicines in the role of Medical Science Liaison. In this field-fa... more
  • 11 Days Ago

  • Praxis Precision Medicines, Inc. Boston, MA
  • Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity Praxis is evolving fro... more
  • Just Posted


Not the job you're looking for? Here are some other Program Executive, Drug Development and Commercial jobs in the Boston, MA area that may be a better fit.

  • Integrated Resources, Inc ( IRI ) Cambridge, MA
  • Job Title: Senior Program Manager Can be hybrid in Cambridge, MA or Princeton, NJ Work Schedule: Mon-Fri 8am-5pm Top Requirements: At least 10 years of dru... more
  • 8 Days Ago

  • Net2Source (N2S) Cambridge, MA
  • Net2Source Inc. is an award-winning total workforce solutions company recognized by Staffing Industry Analysts for our accelerated growth of 300% in the la... more
  • 12 Days Ago

AI Assistant is available now!

Feel free to start your new journey!