What are the responsibilities and job description for the Director Medical Affairs (Contractor) position at PMV Pharmaceuticals, Inc.?
PMV Pharma is a precision oncology company focused on the discovery and development of small molecule therapies targeting p53, a well-characterized tumor suppressor protein mutated in approximately half of all cancers. Leveraging deep scientific expertise and a differentiated approach to reactivating p53, PMV is advancing a pipeline of novel therapies designed to address significant unmet medical needs. The company operates with a lean, highly collaborative team and is progressing toward key clinical and regulatory milestones in support of future commercialization.
Position Overview
The Director, Medical Affairs (Contractor) is currently a project-based role responsible for supporting the development and execution of key Medical Affairs initiatives for the oncology portfolio. This role is engaged to deliver high-priority strategic and operational outputs aligned with clinical, regulatory, and pre-commercial milestones.
Key Responsibilities
- Drive execution of defined components of the Global Medical Affairs Plan
- Partner with cross-functional teams (Clinical Development, Regulatory, Market Access, Commercial) to ensure aligned scientific and communication strategies
- Develop and disseminate scientific and medical materials for healthcare providers, payors, and other stakeholders
- Support advisory board planning and execution aligned with program objectives
- Contribute to KOL engagement strategy and external relationship management
- Monitor and synthesize competitive landscape, clinical data, and scientific trends to inform tactical decision-making
- Provide medical input to support regulatory submissions and clinical development activities
- Ensure all activities comply with applicable regulatory and industry standards (e.g., GxP)
- Support tracking of project-level budgets and Medical Affairs activities, as applicable
Key Deliverables
- Defined components of the Global Medical Affairs Plan
- Advisory board execution and summary outputs
- Scientific communication materials (e.g., slide decks, FAQs, publications support)
- KOL engagement plans and interaction summaries
- Competitive intelligence and medical insights reports
- Contributions to regulatory and clinical milestone activities (e.g., NDA readiness support)
Qualifications
- MD, PhD, or PharmD with significant experience in Oncology Medical Affairs
- ~8–10 years in biotech/pharmaceutical industry, including Medical Affairs leadership or equivalent strategic experience
- Proven ability to independently deliver Medical Affairs strategy and execution in a fast-paced environment
- Strong understanding of regulatory requirements and scientific communication standards
- Demonstrated success in cross-functional collaboration and external stakeholder engagement
- Excellent communication and analytical skills
- Ability to operate with minimal oversight and rapid ramp-up
- Willingness to travel (~20%)
Contract Scope & Engagement Terms
- Project-based, independent contractor role with defined deliverables and timeline
- No direct people management responsibilities
- Operates autonomously while collaborating closely with internal stakeholders
- Not benefit-eligible; engagement structured in accordance with contractor classification guidelines