Scientist II - Preformulation / Solid-State Chemistry

Job Description

Target PR Range: 45-55/hr

• Depending on experience
  
  

Position Summary

We are seeking a highly motivated Temporary Scientist II to join our Preformulation and Solid-State Chemistry group within CMC Drug Product Development. The successful candidate will contribute to the characterization and development of small-molecule new chemical entities (NCEs), focusing on solid-state properties, preformulation assessments, and material sciences to support formulation design and drug product development. This is a temporary position with the opportunity to gain hands-on experience in a fast-paced, collaborative environment.

Key Responsibilities

• Conduct preformulation studies to characterize the physicochemical properties of drug candidates (e.g., solubility, preclinical formulation (solution/ suspension), pKa, log P/D, hygroscopicity, stability).
• Perform solid-state characterization using techniques such as XRPD, DSC, TGA, microscopy, FTIR, SEM, bulk/tapped density, contact angle, and solid-state NMR.
• Under the guidance of a senior scientist, conduct salt, cocrystal, and polymorph screening to enable selection of optimal drug substance forms for development.
• Conduct compatibility and excipient screening studies to support formulation development.
• Work closely with formulation scientists to generate data guiding solid oral dosage form development.
• Analyze, interpret, and document experimental data, ensuring high-quality technical reports.
• Maintain laboratory notebooks and comply with all laboratory safety requirements.
• Present data and findings in team meetings and contribute to scientific discussions.
  
  

Qualifications

Education & Experience

• PhD/M.S. in Pharmaceutical Sciences, Chemistry, Materials Science, or related field with 0-2 years of relevant industry experience; or B.S. with 3-5 years of relevant experience in preformulation or solid-state chemistry.
  
  

Technical Skills

• Hands-on experience with solid-state analytical techniques (XRPD, DSC, TGA, SEM, PLM, Surface area, True density, FTIR, HPLC, NMR spectroscopy).
• Familiarity with solubility, dissolution, and stability testing of drug candidates.
• Understanding of solid-state form screening (salt, cocrystal, polymorph).
• Experience with data analysis and documentation in regulated environments.
• Proficiency with scientific software and instrumentation for material characterization.
  
  

Other Skills

• Strong problem-solving skills and scientific curiosity.
• Excellent organizational and documentation practices.
• Ability to work independently as well as in a multidisciplinary team environment.
• Effective written and verbal communication skills.
  

The Planet Group of Companies is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.