Associate Scientist, HTS & NGS

Notes

• 6-month onsite contract role in Cambridge, MA supporting Korro’s RNA editing platform team. NOT temp-to-perm. Need is project-based/additional support due to increased workload.
• Team is flexible on background: candidates can come from either stronger HTS OR stronger NGS experience. Do NOT need both equally strong; HM/team willing to train the other side.
• Strong preference for biotech/startup candidates who can thrive in lean, fast-paced environments. Large pharma candidates may struggle culturally unless they’ve worked in smaller agile teams.
• RNA therapeutics background preferred, but DNA editing/CRISPR/genomics experience is transferable and acceptable.
• Key target backgrounds: HTS screening, functional genomics, NGS operations, CRISPR screening/platform biology, RNA therapeutics, sequencing workflows.
• Must-have technical areas include some combination of:
• HTS/cell-based assay experience
• NGS workflows/library prep/amplicon sequencing
• Molecular biology techniques (PCR/qPCR, transfection, RNA/DNA isolation)
• Automation/liquid handling exposure preferred
• Personality fit is important: looking for adaptable, detail-oriented, hands-on scientists comfortable wearing multiple hats in a small biotech environment.
• Level is flexible around Associate Scientist level depending on experience/budget.
• Interview process: HM Zoom screen followed by single onsite panel/lab walkthrough (~3 hours total). No presentation required.
• Bill rate target: $90-120/hr.
• Please include in submission:
• specific HTS and/or NGS experience
• automation/liquid handling systems used
  

Duration: 6 months (likely NOT extended)

Bill Rate: Flexible

Location: Cambridge, MA - Onsite

Position Summary: Korro Bio is seeking a highly motivated contract Associate Scientist to join our HTS-NGS operations team and work with an enthusiastic team of highly skilled scientists. The ideal candidate for this lab-based position is committed to delivering high quality results in a timely manner. This is an exciting opportunity to be part of a collaborative team and contribute to the development of next-generation RNA editing technology and therapeutics in a fast-paced biotech company.?

Key Responsibilities

• ???Independently design and execute high-throughput cell-based assays to support oligonucleotide platform and portfolio projects
• Perform amplicon-seq library preparation and quality control, operate and maintain NGS platforms and associated laboratory equipment
• ?Troubleshoot HTS assays, library preparation, and sequencing workflows as needed
• ?Analyze and present HTS-NGS data based on results in a team setting; collaborate with cross-functional teams to support lead discovery
• ?Support NGS scientists in operational tasks, including inventory management, assay development, and operations improvement
• ?Accurately document project and sample information, protocols, and experimental details through an Electronic Lab Notebook (ELN)
  
  

Required Qualifications

• ???MS with 3 years or BS with 5 years of experience in molecular biology, cell biology, or related field
• ?1 years of hands-on experience with high-throughput assays and automated workflows
• ?Experience with cell culture techniques, including plating and transfection in 96/384-well formats
• ?Experience with NGS assays: amplicon-seq and RNA-seq, including primer design, library preparation, quantification, and data quality control
• ?Demonstrated expertise in molecular biology techniques: RNA/DNA isolation, transfection, PCR/qPCR, gel electrophoresis
• ?Familiarity with liquid handling systems (e.g., Viaflo96/384, HiRes/Certus Flex, Tempest) is highly preferred
• ?Hands-on experience with next-generation sequencing platforms and equipment including Illumina (MiSeq i100), Qubit, Tape Station, and Fragment Analyzer is highly preferred
• ?Experience with LIMS systems (Benchling) and project management tools (Jira/Confluence)??
• ?Strong troubleshooting skills and ability to suggest and implement new solutions independently
• ?Excellent written and verbal communication skills with attention to detail
• ?Ability to thrive in a fast-paced and evolving environment ??