Downstream Purification Scientist / Pharma Biologics (PT556)

Position Details:

Our client, a world-leading Pharmaceutical Company in Andover, MA is currently looking for a Downstream Purification Scientist to join their expanding team.

Job Title: Downstream Purification Scientist / Pharma Biologics

Duration: 18 months contract, extendable up to 36 months

Location: Andover, MA

Note:

The client has the right-to-hire you as a permanent employee at any time during or after the end of the contract.

You may participate in the company group medical insurance plan

Job Description: (Required):

Position Summary/ Position Responsibilities

We are looking for a Downstream Scientist to join the Manufacturing Sciences and Technology (MSAT) organization at Pharmaceutical based out of Andover, MA.

The MSAT downstream purification team supports purification process development and optimization for commercial processes and next generation process development.

This person will be expected to develop and qualify purification techniques, ensure the proper and timely execution of purification processing, and perform scale-down purifications of biologics using a variety of unit operations, such as precipitation, depth filtration, TFF, and chromatography.

Process development and characterization for vaccine programs and second-generation processes using various purification techniques.

Plan, design, and execute downstream experiments to enable technology transfer of vaccine programs and second-generation purification processes.

Operation and maintenance of downstream equipment and associated analytical tools.

Data analysis, technical writing, reporting, and presenting to internal teams.

Support manufacturing investigations and purification process troubleshooting.

Drive lab improvement, 5S, standardization initiatives within department.

Plan, prepare, execute, and conclude critical vaccine material production campaigns.

Collaborate with project team to divide responsibilities and communicate results.

Emphasize teamwork and cross functional learning/training of new skills.

Education And Experience

Bachelor's degree in a relevant discipline with at leaset 3 years of applicable bioprocess experience.

Experience with mRNA drug substance process (such as in-vitro transcription reactions), Enzyme based process, and purification of biomolecules (such as Enzymatic reactions, AKTA, UF/DF, Column Chromatography)

Famililary working in GxP cross matrix organizations

Lab-scale purification process development and troubleshooting experience with standard downstream equipment (e.g. AKTAs, Repligen TFF, etc...)

Experience and knowledge of templated processes such as mAbs

Experience with mRNA Lipid Nano Particle (LNP) formulation and final Drug Product (DP)