What are the responsibilities and job description for the PET Radiochemist position at PHARMALOGIC?
Division │ Department: PharmaLogic
Position Title: PET Radiochemist
Reports To: PET Facility Manager
Role Summary:
The PET Radiochemist will play an essential role in the development, implementation, and validation for new radiopharmaceuticals, radiochemicals and isotope production. The position will have hands-on experience with radiochemistry synthesis, purification, and formulation for invivo imaging and biodistribution studies; executing studies in parallel; and working alongside other laboratory scientists.
Job Responsibilities and Duties:
1. Responsible for production of PET radiotracer:
- Synthesis of generic and novel PET radiopharmaceuticals.
- Purification of small and large molecules.
- Support analytical methods for HPLC, GC and TLC.
- Release criteria for imaging studies.
- Dose formulation.
2. Operate and maintain automated radiochemistry synthesis units.
3. Maintain experience with broad range isotopes and labeling methods including:
- Radioiodination.
- F-18 small molecule and click chemistries.
- Radiometal chelation.
4. Work with appropriate personnel to install, qualify and maintain equipment on- site.
5. Operate and calibrate laboratory instruments and equipment to produce accurate results.
6. Assist with improvement of current cGMP and non-GMP processes.
7. Follow all SOP guidelines for QC release testing of radiopharmaceutical product, raw material, finished and semi-finished product, environment and facilities.
8. Maintain clean and safe work environment, performing radiation safety duties in compliance with safety and pharmaceutical regulations.
9. Maintain accurate production and test/validation results.
10. Perform other job-related duties as assigned.
Job Requirements │ Skills │ Education:
- Requires a bachelor’s degree in Chemistry, Radiology, Nuclear Medicine Nuclear Physics, Nuclear Engineering or related field.
- Master’s or PhD degree in Chemistry, Radiology, Nuclear Medicine, Nuclear Physics, Nuclear Engineering or relate field preferred.
- Familiarity with a GMP manufacturing environment and working with FDA and FDA cGMP regulations required. Knowledge of molecular imaging techniques and pharmaceutical study design and execution desired.
- Experience with laboratory procedures and radiochemistry techniques (separation techniques – SPE) and analytical method, equipment (ICP-MS, ICP- OES, GC, TLC, and radiometric measures) highly favored.
- Experience with HPLC, radiochemistry synthesis, US FDA cGMP, Radiation Safety Principles, Isotopes production and analytical equipment troubleshooting and maintenance a plus.
- Superior teamwork, multi-tasking and time/project management skills.
- Excellent communication, analytical, problem solving, presentation and computer/pc skills (including proficiency in Microsoft Suit and related software).
· Ability to work varying shifts and travel up to 50%.
Physical and Intellectual Requirements:
Required are a mechanical aptitude; manual dexterity for manipulating small items; ability to lift between 16 to 50 lbs. and to handle frequent crawling, stooping, crouching and kneeling; ability to analyze situations, set priorities and meet deadlines while maintaining attention to detail in a fast-paced and dynamic environment; effective organizational skills; a commitment to continuous learning; an ability to work well both independently and as part of a team.
Job Type: Full-time
Pay: From $50,000.00 per year
Benefits:
- 401(k)
- Dental insurance
- Health insurance
- Health savings account
- Life insurance
- Paid time off
- Retirement plan
- Vision insurance
Schedule:
- 8 hour shift
- Night shift
Education:
- Bachelor's (Preferred)
Experience:
- Radiochemistry: 2 years (Preferred)
Work Location: One location
