Senior Scientist- – In Vivo Pharmacology

Use Your Power for Purpose

At Pfizer, our purpose is to deliver breakthroughs that transform patients' lives. Central to this mission is our Research and Development team, dedicated to translating advanced science and innovative technologies into impactful therapies and vaccines. Whether you are engaged in discovery sciences, ensuring the safety and efficacy of drugs, or supporting clinical trials, you will leverage cutting-edge design and process development capabilities. Your efforts will accelerate the delivery of best-in-class medicines to patients globally, fulfilling Pfizer's commitment to making a meaningful difference in healthcare.

Role Summary

Within the Internal Medicine Research Unit (IMRU), one of the key focus areas of the Metabolism group is identifying novel therapies to improve metabolic outcomes in patients suffering from obesity. Our goal is to identify a team focused candidate with a deep mechanistic understanding of energy metabolism in the context of metabolic dysfunction. The scientific focus of this lab-based role is to identify critical metabolic pathways in obesity and weight maintenance using in vivo models with the goal of developing novel therapies. In addition to drug discovery interests, publication in high-impact journals and presentation of research is encouraged. The candidate will have daily interactions with a team of creative and innovative scientists in a supportive environment for rigorous scientific and drug development training. Strong self-motivation, extensive in vivo experience, excellent communication interpersonal skills, and the ability to work independently and as part of a team are essential.

Role Responsibilities

• Apply creative thinking and scientific expertise to the formulation of strategies to identify and validate therapeutic targets in key areas of interest to the Internal Medicine Research Unit.
• Maintain an awareness of ‘cutting edge’ scientific and technical developments in preclinical to clinical translation and apply these where possible to advance the portfolio programs.
• Conceptualize, design and execute in vivo studies (including preparation, data collection, interpretation, and presentation)
• Quantify and translate experimental results to advance the understanding of how metabolic pathways and complex physiological systems are altered by diseases and how they respond to therapeutic interventions
• Present research findings to Pfizer colleagues, including leadership, and the external scientific community through publication in peer-reviewed journals and talks and posters at scientific meetings.
• Ensure that all research/discovery work is conducted with highest quality and ethical guidelines and in accordance with relevant regulatory, QC, and compliance guidelines.
• Mentor junior scientists in developing skills essential to the execution of rigorous scientific research
  
  

Qualifications

• PhD with post-doc experience in relevant field, M.S. with 7 years relevant experience, OR B.S. with 9 years of relevant experience
• Demonstrated ability to review critically available data and to think creatively in formulating novel hypotheses.
• Successful record of scientific accomplishments as indicated by scientific publications and presentations.
• Deep expertise in preclinical rodent physiology and pharmacology
• The candidate should be able to work independently as well as with an interdisciplinary team of scientists in a highly collaborative environment.
• Demonstrated ability to contribute to multiple projects in parallel with learning agility and scientific rigor.
• Strong written/verbal communication skills and ability to collaborate effectively with scientists working in other disciplines.
• Strong self-motivation
  
  

Additional Information:

• Work Location Assignment: On Premise
• Last Day to Apply: October 3, 2025
  
  

The annual base salary for this position ranges from $90,900.00 to $151,500.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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Research and Development