Application Systems Administrator III (M365/SharePoint)

POSITION SUMMARY

The Application Systems Administrator III (M365/SharePoint) is responsible for the administration, configuration, and support of Microsoft 365 and SharePoint Online platforms within a regulated pharmaceutical manufacturing environment. This position ensures that collaboration, document management, and workflow tools are optimized to meet the needs of the operations, quality, engineering, and compliance teams while adhering to GxP, CMMC and other regulatory requirements. The Administrator plays a key role in managing data stores and their security, maintaining the validated state of systems, and implementing policies to support these systems. The Administrator will also work closely with other departments working on projects related to applications and systems that they will support.

PRIMARY RESPONSIBILITIES

System Administration & Configuration

• Manages and maintains Microsoft 365 services, including SharePoint, Teams, OneDrive, and other related or integrated software.
• Configures and administers SharePoint sites, libraries, workflows, permissions, and metadata to support manufacturing, QA, QC, validation, engineering, and corporate functions.
• Develops and enforces standards, security models, and best practices for data architecture and content management.
• Administers other collateral systems appropriate to the role, i.e. backup/restore systems, authentication systems, user management, printing, etc.

Compliance & Validation Support

• Maintains the validated state of systems by following change control, documentation, and testing procedures.
• Partners with Quality Assurance to support audits, CAPAs, and regulatory inspections.

Operational Support & Troubleshooting

• Provides advanced troubleshooting and resolution for system and user issues within M365/SharePoint and other related software solutions.
• Supports integration of M365/SharePoint with other enterprise applications as needed (e.g., LIMS, ERP, etc.).

Enhancements & Projects

• Leads migrations, upgrades, and implementation of new M365 services and features.
• Collaborate with business stakeholders to gather requirements and design secure solutions
• Automates administrative and operational tasks using PowerShell, Power Automate, etc.
• Leads ongoing reviews of business processes, anticipates requirements, uncovers areas for improvement, and develops and implements solutions.

Training & User Support

• Provides end-user training, documentation, and support to promote adoption of M365/SharePoint tools across the organization.
• Acts as a subject matter expert for our MS services and related software solutions.

Cross-Functional Collaboration

• Works with other teams in the organization to align system capabilities with business needs.
• Partners with IT Security and Compliance teams to ensure adherence to cybersecurity and data protection standards.
• Works with Microsoft and third-party vendors to resolve issues and implement solutions.

KNOWLEDGE, SKILLS, ABILITIES

Required:

• A solid working knowledge of networking principles, including the OSI and TCP/IP network models, subnetting and VLANs, ports and protocols, routing, firewalling, WiFi, VPN’s, etc.
• Microsoft 365 Ecosystem – Deep understanding of M365 services, including Exchange Online, Teams, OneDrive, Power Platform, and SharePoint.
• SharePoint Administration – Knowledge of site collections, site architecture, permissions models, workflows, and governance best practices.
• Cloud and Hybrid Environments – Understanding Azure Active Directory, authentication (SAML, OAUth, SSO, MFA), and hybrid SharePoint/Exchange environments.
• Information Security & Compliance – Familiarity with data governance, retention policies, and compliance features in M365.
• System Integration – Knowledge of APIs, connectors, and integration of M365/SharePoint with third-party or line-of-business applications.
• Automation & Scripting – Proficiency in PowerShell and Power Automate for process automation, reporting, and administrative efficiency. System Optimization – Ability to identify inefficiencies and propose improvements to enhance platform performance and user adoption.
• Collaboration & Communication – Strong ability to translate technical concepts into business-friendly language and provide end-user support/training.
• Collaboration & Teamwork – Strong, collaborative relationship management and interpersonal skills required to quickly gain confidence of stakeholders and team members. Demonstrates a bias towards action, the ability and willingness to give and receive constructive feedback, is comfortable working within a diverse team and across multiple functions, exhibits a consistently constructive attitude, and is adaptable and at ease with handling unexpected changes and challenges.
• Project Management – Skilled in planning, coordinating, and executing upgrades, migrations, and implementation projects in order to complete assignments on-time and on-budget.
• Solid English language communication skills, both oral and written, are required for this highly collaborative role.
• Adheres to all applicable regulations and requirements including compliance with internal SOPs, GMP, Health and Safety, WISHA/OSHA, regulatory compliance, company policies, and employment-related laws and statutes.

EXPERIENCE & EDUCATION

Required:

• High School diploma or GED
• 3 years of progressively responsible, relevant experience supporting M365 and SharePoint systems.
• 5 years of progressively responsible experience as an IT administrator or in a similar role.

Preferred:

• Bachelor’s degree in information systems-related field.
• Experience in a regulated manufacturing environment (Biotech, Financial, etc.)
• Previous SQL/DBA experience.

PTx is committed to the principles of competitive and pay equity for all of our Partners. The current pay range for this position is $97,000 - $128,000: Offers are made within the base pay range applicable at the time. Your salary will vary depending on several factors including your qualifications and experience.

In addition to medical, dental, vision, FSA/DCA, HRA, disability, and life insurance coverage, all full-time, regular Partners enjoy a casual, and Hybrid or Remote workplace program for many roles. We offer a terrific compensation/benefits/perks package which includes pre-IPO options, annual cash bonuses, 401k matching, free parking or Seattle-area ORCA pass, tuition assistance, plus rewards for achievement and contribution. To support a healthy work-life balance we also provide a gym subsidy, wellness participation programs, and a generous vacation, sick, and holiday paid time off program in addition to a paid shutdown between the Christmas and New Year’s holidays.

Partner Therapeutics is an Equal Opportunity Employer and does not discriminate on the basis of race, color, religion, sex, age, national origin, veteran status, marital status, sexual orientation, gender identity, disability or any other category prohibited by local, state, or federal law. This policy applies to all aspects of employment, including recruitment, placement, promotion, transfer, demotion, compensation, benefits, social and recreational activities, and termination.