What are the responsibilities and job description for the Global Application Support Engineer position at Orise?
Job Description
Position Summary
We are seeking a mid-level Application Support Engineer to support the expansion of our Global Application Support on-site in Indianapolis, IN. This role is ideal for an engineer with strong SQL and application troubleshooting experience, who can independently support production applications, analyze data issues, and partner with global teams to ensure system reliability in a regulated pharmaceutical environment.
This person must embrace a team-first approach by sharing responsibilities, coordinating efforts, and stepping in where needed to maintain momentum. Ensures timely completion of work through strong communication, mutual accountability, and a commitment to shared goals.
Key Responsibilities:
Required Qualifications
Position Summary
We are seeking a mid-level Application Support Engineer to support the expansion of our Global Application Support on-site in Indianapolis, IN. This role is ideal for an engineer with strong SQL and application troubleshooting experience, who can independently support production applications, analyze data issues, and partner with global teams to ensure system reliability in a regulated pharmaceutical environment.
This person must embrace a team-first approach by sharing responsibilities, coordinating efforts, and stepping in where needed to maintain momentum. Ensures timely completion of work through strong communication, mutual accountability, and a commitment to shared goals.
Key Responsibilities:
- Provide Tier 2 / Tier 3 application support for critical manufacturing and enterprise applications, including incident response, troubleshooting, and root cause analysis
- Use SQL to analyze application data, investigate issues, validate fixes, and support reporting or data corrections as needed
- Serve as a technical escalation point for complex application and data-related issues, coordinating with global support teams and developers
- Responsible for the full lifecycle management of global applications supporting pharma production operations, including rollout, configuration, validation, patching, and version upgrades. Coordinates feedback from site users and operational stakeholders, translating needs into actionable requirements for developers to drive future product development.
- Partner with business users, IT, and engineering teams to identify recurring issues, propose improvements, and enhance application performance and stability
- Create and maintain support documentation, SOPs and knowledge base articles
- Ensure compliance with GxP, data integrity, change management, and cybersecurity requirements
- Develops, documents, and executes comprehensive test cases for global applications used across pharmaceutical operations, ensuring compliance with validation standards and regulatory requirements. Collaborates with cross functional teams to verify functionality, identify defects, and support timely resolution
Required Qualifications
- Bachelor’s degree in Engineering, Computer Science, Information Systems, or a related technical field (or equivalent experience)
- 3–6 years of experience in application support, systems support, or manufacturing IT
- Strong hands-on experience with SQL (querying, troubleshooting data issues, performance analysis)
- Experience supporting applications in pharmaceutical, biotech, or other regulated manufacturing environments
- Familiarity with incident, problem, and change management processes (ITIL or similar)
- Strong communication skills and ability to work effectively in an on-site, cross-functional environment
- Experience supporting manufacturing execution, quality and/or laboratory systems
- Knowledge of GxP validation, audit support, and regulated change control
- Experience working with SQL Server, Oracle, or similar relational databases
- Exposure to global application support models and follow-the-sun operations