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Director, Accounting & Technical Accounting

Orca Bio
Menlo Park, CA Full Time
POSTED ON 5/9/2026
AVAILABLE BEFORE 7/8/2026

More than one million people in the United States today are fighting blood cancer. While a traditional allogeneic stem cell transplant has been the best hope for many, the transplant itself can prove fatal or lead to serious conditions, such as graft vs. host disease. Orca Bio is a late-stage biotechnology company redefining the transplant process by developing next-generation cell therapies with the goal of providing significantly better survival rates with dramatically fewer risks. With our purified, high-precision investigational cell therapies we hope to not only replace patients' blood and immune systems with healthy ones, but also restore their lives.


The Director, Accounting & Technical Accounting will play a critical leadership role within the controllership function at Orca Bio. This individual will oversee key accounting and reporting activities, including but not limited to financial reporting, general ledger accounting, and technical accounting matters.

The ideal candidate thrives in a fast-paced, high-growth biotech environment and brings a hands-on, “roll-up-your-sleeves” mindset. This role requires strong technical expertise, sound judgment, and the ability to identify and resolve issues proactively while effectively communicating with cross-functional stakeholders. A deep commitment to Orca Bio’s mission and values is essential.

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Essential Duties & Key Responsibilities
  • Partner with the Controller to support the financial close process, including review of journal entries and account reconciliations.
  • Lead trial balance reviews, analyze variances, and ensure timely resolution of discrepancies.
  • Support and coordinate the annual external audit process and related audit requests.
  • Lead clinical trial accounting activities, including developing and maintaining study-level accounting models, accrual methodologies, and cost tracking processes to ensure accurate and timely recognition of clinical research expenses.
  • Assist in annual testing of process- and company-level internal controls, as assigned.
  • Ensure general ledger accounting complies with U.S. GAAP and provide guidance on emerging technical accounting issues and new accounting standards.
  • Oversee stock administration in coordination with the Company’s third-party service provider, ensuring the accuracy of stock transactions, and managing equity accounting in alignment with financial reporting requirements.
  • Manage investor reporting in accordance with reporting obligations, ensuring accuracy, timeliness, and consistency with internal financial reporting and external requirements.
  • Collaborate closely with the accounting team to maintain best-in-class performance and continuous improvement.
  • Partner effectively with cross-functional teams and executive leadership to support operational and strategic initiatives.


Required & Preferred Qualifications
  • Bachelor’s degree in accounting, Business, Economics, or a related field required; CPA license strongly preferred.
  • 12 years of accounting experience with 8 years managing financial reporting at a publicly traded or private company. Biotech or life science industry experience is strongly preferred.
  • A proven leader with strong technical capabilities with deep expertise in GAAP and SEC reporting; demonstrated experience in the preparation of relevant SEC/external filings.
  • Experience managing accounting close process and performing related analyses.
  • Proven experience developing sound financial analyses, explanations and recommendations.
  • Excellent written and verbal communication skills and experience developing and making presentations to C-level executives.
  • Proven self-starter with experience improving finance functions; ability to work well in a team environment and across organizational disciplines.
  • Understanding SOX/404 compliance requirements.


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$195,000 - $230,000 a year
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The anticipated annual salary range for this job is based on prior experience in the role/industry, education, location, internal equity, and other job-related factors as permitted by law. For remote-based positions, this range may vary based on your local market. Full-time employment positions will also be eligible to receive pre-IPO equity and annual bonus, in addition to competitive medical, dental, and vision benefits, PTO, 401(k) plan, life and accidental death and disability coverage, and parental leave benefits. Other perks include subsidized daily lunches and snacks at our on-site locations.

 

Who we are

 

We are driven by a passion for science and compassion for patients. We act with urgency to ensure our treatments are one day accessible to all who need them.

 

We live by our core values of passion, courage, and integrity. Excellence in our work means the chance to unlock a better quality of life for our patients, and with that comes tremendous responsibility.

 

We innovate on a path that hasn’t been paved. We embrace an entrepreneurial spirit and take calculated risks to achieve our mission. We aren’t afraid to ask “why not” and challenge the status quo.

 

We maintain a start-up culture of camaraderie and leadership by example, regardless of title.

 

We’re proud to be an equal opportunity employer, and recognize that celebrating our differences creates stronger, lasting solutions that better serve our team, our patients and their healthcare providers.

 

Notice to staffing firms

 

Orca Bio does not accept resumes from staffing agencies with which we do not have a written agreement and specific engagement for a particular opening. Our employment activities, inquiries and offers are managed through our HR/Talent team, and all candidates are presented through this channel only. We do not accept unsolicited resumes, and we rarely outsource recruitment.

Salary : $195,000 - $230,000

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