Director, AI Innovation & Partnerships

We are a fast-growing and dynamic organization seeking a DirectorAI Innovation & Partnerships to join our team. The Director AI Innovation & Partnerships builds and directs a portfolio of cross-functional AI use cases across the company, including discovery through clinical development, regulatory/QA, CMC, Commercial, and Corporate functions. The role translates scientific and business needs into technical capabilities and automated solutions. Position is responsible for developing and managing strategic external AI-focused partnerships to advance the company’s programs and functions. Position reports to Associate VP of Structural Biology with dotted line reporting into CBDO and CEO.

Good things are happening at Omeros!

Who is Omeros?

Omeros is an innovative biotechnology company that discovers, develops, and commercializes first-in-class small-molecule and protein therapeutics for large-market and orphan indications, with particular emphasis on complement-mediated diseases, cancers, and addictive or compulsive disorders. Omeros’ lead lectin pathway inhibitor YARTEMLEA®, which inhibits the pathway’s effector enzyme MASP-2, is FDA-approved for the treatment of hematopoietic stem cell transplant-associated thrombotic microangiopathy (TA-TMA) in adult and pediatric patients ages two years and older, with a planned U.S. launch in January 2026. A marketing authorization application for YARTEMLEA in TA-TMA is currently under review by the European Medicines Agency, with a decision expected in mid-2026. OMS1029, Omeros’ long-acting MASP-2 inhibitor, has successfully completed Phase 1 clinical trials.

Under a recently announced asset purchase and licensing agreement, Novo Nordisk acquired global rights to zaltenibart (formerly OMS906), a MASP-3 inhibitor in clinical development for PNH and other alternative pathway indications, along with associated intellectual property and related assets. Omeros’ pipeline also includes OMS527, a phosphodiesterase 7 inhibitor in clinical development for cocaine use disorder and fully funded by the National Institute on Drug Abuse, as well as a growing portfolio of novel molecular and cellular oncology programs. For more information about Omeros and its programs, visit www.omeros.com.

What are your job responsibilities?

Areas of specific responsibility include the following:

• Explores, identifies & prioritizes opportunities and solutions for a portfolio of AI/data initiatives across Omeros
• Guides the development and implementation of internal objectives, operating model, governance structure, and related success metrics for the deployment and management of AI and related automated tools
• Leads AI and automation projects from ideation through execution, driving internal adoption and maturation of AI tools in collaboration with IT
• Aligns stakeholders across Research, IT, Regulatory/QA, CMC, Clinical, Commercial, and Corporate functions
• Guides the translation of biomedical, product, and business questions into addressable computational and AI approaches
• Analyzes and monitors technical and market trends for driving productivity, collaboration, and business growth through AI and related automated tools
• Cultivates and maintains a strong network to build an external innovation pipeline. Identifies, evaluates, and onboards collaborators to create mutually beneficial partnerships
• Supports alliance management, cross-functional coordination, and/or special initiatives
• Represents the company at AI-related industry conferences, scientific meetings, and partnership discussions to promote Omeros and foster collaboration opportunities

What education and experience do you need?

• Advanced degree (PhD, MA, MBA, or equivalent) preferred, or significant relevant industry experience and business acumen
• 10 years in life sciences partnership leadership, digital transformation, program management, and/or strategy consulting with measurable outcomes
• Ability to think strategically and analytically, with a track record of identifying, evaluating, and capitalizing on collaborative opportunities
• Design Thinking and innovation skills strongly preferred
• Strong project/portfolio management skills, with the ability to manage multiple initiatives simultaneously and work across cross-functional teams
• Excellent interpersonal, networking and communication skills, with the ability to engage effectively with executives, scientists, company team members, and external stakeholders
• Understanding of the drug development process, including early-stage discovery through clinical development/regulatory affairs and commercialization
• Working fluency in AI/ML concepts, data foundations, and delivery patterns (hands-on experience highly preferred, and must be able to steer efforts competently)
• Excellent written/oral communication skills

Behavioral Competencies Required:

• Versatility to thrive in a fast-paced, dynamic environment
• Demonstrated ability to build partnerships and to coordinate across multiple teams to meet challenging timetables
• Strong interpersonal and management skills with the ability to maintain positive relationships with management, peers, subordinates, and external constituents

Compensation and Benefits:

Omeros is proud to offer a competitive total compensation package designed to support the lives of our employees and their families. The wage scale for Director AI Innovation & Partnerships position is $215,000-$235,000. Salaries will be determined based on knowledge, skills, education, and experience relevant to the role. Employees are offered medical, dental, vision, life insurance, and a 401(k) plan with a company match. Employees accrue three weeks of vacation and 80 hours of sick time on an annual basis and receive twelve paid holidays throughout the calendar year. This position is eligible for incentive and stock options. To learn more about Omeros, please visit www.omeros.com.

Omeros is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to status as a protected veteran or a qualified individual with a disability, or other protected status such as race, religion, color, national origin, sex, age, marital status, or any other factor determined to be unlawful by federal, state, or local statutes.

It is our policy to provide reasonable accommodation to anyone with a disability who needs assistance completing the job application process. If you need assistance, you can either send an e-mail to hr@omeros.com or contact Omeros, asking for Human Resources, at (206) 676-5000.