Demo

Principal Scientist, Mass Spectrometry

Novartis
Emeryville, CA Full Time
POSTED ON 11/3/2025
AVAILABLE BEFORE 1/3/2026

Summary

We are looking for an enthusiastic, curious, and highly motivated individual with experience in bioanalytical mass spectrometry and MALDI imaging mass spectrometry to join our Analytical Chemistry group in Emeryville, CA. As an analytical expert you will play a key role in advancing our cutting-edge research and drug discovery programs as well as driving the evaluation and implementation of innovative technologies. This role involves collaboration with scientists and project teams across disease areas.

About the Role

Internal job title: Principal Scientist I

Position Location: Emeryville, CA, onsite #LI-onsite

We are looking for an enthusiastic, curious, and highly motivated individual with experience in bioanalytical mass spectrometry and MALDI imaging mass spectrometry to join our Analytical Chemistry group in Emeryville, CA. As an analytical expert you will play a key role in advancing our cutting-edge research and drug discovery programs as well as driving the evaluation and implementation of innovative technologies. This role involves collaboration with scientists and project teams across disease areas.

Key responsibilities:

  • Collaboration across Biomedical Research sites on the application of MALDI Imaging MS technology for drug discovery support
  • Lead design and execution of drug and metabolite tissue distribution experiments using MALDI Imaging MS in support of small molecule drug discovery
  • Conduct LC-MS assays for plasma and tissue quantitation in support of PK and PK/PD studies
  • Perform tissue cryo-sectioning and MALDI sample preparation
  • Implementation of state-of-the-art MS systems for data acquisition and analysis
  • Develop methods to evaluate the tissue distribution of new modalities including RNA therapeutics, protein degraders, and antibody drug conjugates
  • Data interpretation, report preparation and presentation of results to discovery project teams
  • Effectively manage timelines and work closely with team members and customers in an international setting
  • Promote innovative technologies and cross-disciplinary research to enhance the group’s analytical capabilities

Essential Requirements:

  • Ph.D. in analytical chemistry, biochemistry, or related field with a minimum of 2 years of postgraduate experience
  • Experience using analytical chemistry technologies including mass spectrometry
  • Experience in quantitative analysis in biological matrices using mass spectrometry
  • Experience with tissue cryo-sectioning, MALDI sample preparation, and imaging data analysis
  • Critical and creative problem-solving skills with independent thinking.
  • Strong written and verbal communication skills along with the ability to work effectively on matrix teams

The salary for this position is expected to range between $103,600 and $192,400 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

To learn more about the culture, rewards and benefits we offer our people click here.

Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture

Join our Novartis Network: Not the right Novartis role for you? Sign up to our talent community to stay connected and learn about suitable career opportunities as soon as they come up: https://talentnetwork.novartis.com/network

Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards

EEO Statement:

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility & Reasonable Accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to [email protected] or call 1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.


Division
Biomedical Research
Business Unit
Universal Hierarchy Node
Location
USA
State
California
Site
Emeryville
Company / Legal Entity
U175 (FCRS = US175) Novartis Institutes for BioMedical Research, Inc.
Functional Area
Research & Development
Job Type
Full time
Employment Type
Regular
Shift Work
No

Salary : $103,600 - $192,400

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Principal Scientist, Mass Spectrometry?

Sign up to receive alerts about other jobs on the Principal Scientist, Mass Spectrometry career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$136,838 - $174,985
Income Estimation: 
$165,358 - $212,143
Income Estimation: 
$82,813 - $108,410
Income Estimation: 
$120,989 - $162,093
Income Estimation: 
$74,806 - $91,633
Income Estimation: 
$71,928 - $87,026
Income Estimation: 
$145,337 - $174,569
Income Estimation: 
$130,030 - $173,363
Income Estimation: 
$194,895 - $259,743
Income Estimation: 
$192,057 - $260,440
Income Estimation: 
$249,515 - $311,938
Income Estimation: 
$155,477 - $213,492
Income Estimation: 
$155,477 - $213,492
Income Estimation: 
$161,172 - $205,272
Income Estimation: 
$120,254 - $158,147
Income Estimation: 
$225,010 - $318,974
Income Estimation: 
$208,337 - $274,406
Income Estimation: 
$68,606 - $89,684
Income Estimation: 
$88,975 - $120,741
Income Estimation: 
$68,121 - $81,836
Income Estimation: 
$71,928 - $87,026
Income Estimation: 
$125,958 - $157,570
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at Novartis

Novartis
Hired Organization Address Dakota, SD Full Time
Job Details Job Description Summary The high-throughput biology group in Novartis San Diego is seeking a technologically...
Novartis
Hired Organization Address Omaha, NE Full Time
Summary Access and Reimbursement Manager (ARM) is a field-based role that proactively provides in person (or virtual as ...
Novartis
Hired Organization Address Las Vegas, NV Full Time
Summary Location: Remote- Las Vegas, NV The Associate Director, Access & Reimbursement, NPS (Novartis Patient Support) C...
Novartis
Hired Organization Address Paducah, KY Full Time
Summary Access and Reimbursement Manager (ARM) is a field-based role that proactively provides in person (or virtual as ...

Not the job you're looking for? Here are some other Principal Scientist, Mass Spectrometry jobs in the Emeryville, CA area that may be a better fit.

Principal Data Scientist

Abbott, Alameda, CA

Principal Data Scientist

1020 Abbott Diabetes Care Inc, Alameda, CA

AI Assistant is available now!

Feel free to start your new journey!