What are the responsibilities and job description for the Cell Manufacturing Technologist (cGMP) position at Northwest Biotherapeutics?
About Northwest Biotherapeutics
Northwest Biotherapeutics, Inc is a clinical stage biotechnology company focused on the development of personalized dendritic cell (DC) cancer vaccines designed to treat a broad range of solid tumor cancers. We are seeking a Cell Manufacturing Technologist to join our cGMP DC production unit in Pittsburgh. This role will manufacture within ISO 7 clean rooms under cGMP conditions. This role is critical to the manufacturing of DC vaccines for clinical applications.
Introduction
Participates in the manufacturing process and process improvements, laboratory projects, and experiments. Performs a variety of specialized technical tasks according to established methodology.
Key Responsibilities
- Prepares and sets up materials and equipment.
- Performs cell culture processes from leukapheresis through DC culture, including antigen loading, maturation, cryopreservation, and final formulation of cellular products for patient administration.
- Records results, performs calculations and compiles data.
- Maintains accurate documentation of all manufacturing steps in compliance with cGMP regulations and approved clinical protocols.
- Maintains equipment and arranges for servicing.
- Ensures the cleanliness and safety of the work area.
- Maintains inventory.
- Keeps abreast of new developments in the field to update skills and knowledge.
- Contributes to the development and revision of Standard Operating Procedures (SOPs).
- Ensures integrity of the manufacturing process by completing batch records and adhering to regulatory requirements.
- Trains and supports other team members following completion of training.
- Collaborates with R&D and cGMP operations at NWB’s additional sites.
Qualifications
- Prior laboratory experience with adherence to protocols and SOPs.
- Experience working under cGMP conditions, preference will be given to candidates with FACT accredited facility experience.
- Experience with human cell culture, with preference given to candidates with dendritic cell experience.
- Strong record-keeping and documentation skills.
- Experience with MS Office used in the preparation of scientific reports and presentation of data.
- Ability to work collaboratively in a regulated environment and contribute to process improvements.
- Excellent English, spoken and written
- Excellent communication and interpersonal skills
- Ability to work independently or with teams with minimal supervision
Growth Opportunities
This position offers pathways to future supervisory roles, providing opportunities for professional development within NWB’s expanding operations.
Compensation & Benefits
- Competitive salary and benefits
- Equity Compensation Plan:
Eligible for stock options and/or other securities tied to achievements and milestones.
How to Apply
Interested candidates should direct inquiries and applications to:
Careers@NWBio.com
Only individuals selected for interviews will be contacted.
Applications may be used to fill other current and future opportunities.