Senior Director, Commercial - Isotopes

Overview

Join the best radiopharmaceutical company in the world!

If you’re looking to make an impact while building a meaningful career in a specialized, fast-growing field, NorthStar Medical Radioisotopes is the place to do it. NorthStar Medical Radioisotopes is a growing, commercial-stage company focused on advancing patient care by providing therapeutic radioisotopes and novel radiopharmaceuticals to detect and treat cancer.

At the forefront of NorthStar’s technological innovation is scientific excellence, using first-in-kind electron accelerator technology and integrated campus capabilities to drive progress in radiopharmaceutical manufacturing. Our work is driven by a meaningful mission—advancing life-saving radiopharmaceutical development and ensuring a reliable supply of critical medical isotopes for patients in need. As a rapidly growing organization operating on the cutting edge of science, we offer exceptional career growth and professional development opportunities, supported by world-class facilities and a competitive benefits package.

Position

The Senior Director, Commercial – Isotopes is a senior commercial executive responsible for building, scaling, and leading NorthStar’s isotope  business as a durable growth engine. This role owns the commercial strategy, revenue performance, and long-term value creation of the isotope portfolio, spanning diagnostic, therapeutic, and emerging nuclear medicine applications.

This leader will operate as a general manager mindset—balancing near-term revenue delivery with long-range strategic positioning, production capacity optimization, pricing discipline, and portfolio prioritization. The role requires strong business judgment, comfort navigating ambiguity, and the ability to make informed trade-offs in a capital- and capacity-constrained environment.

Responsibilities

Commercial Growth, Strategy & Business Ownership:

• Own full revenue forecast and accountability for the isotope production portfolio, including revenue growth, pricing discipline, margin performance, and long-range pipeline health.
• Develop and execute multi-year commercial strategies (3–5 year horizon) aligned with enterprise priorities, capital investments, and capacity expansion plans.
• Translate corporate strategy into actionable market segmentation, account prioritization, and investment decisions.
• Lead executive-level relationships across pharmaceutical, radiopharmacy, and other customers, serving as a trusted commercial and strategic partner—not just a commodity provider.
• Apply market intelligence, competitive analysis, and customer insights to inform where to play / how to win decisions across diagnostic, therapeutic, and other isotope segments.
• Make data-driven recommendations on isotope development, production allocation, and partnership opportunities, including evaluating strategic fit, supply chain risk, regulatory complexity, and long-term return on investment.

Deal Leadership, Contracting & Commercial Excellence:

• Lead complex, high-value negotiations for long-term supply agreements, framework pricing arrangements, distribution partnerships, and security-of-supply commitments.
• Establish and enforce value-based pricing strategies that reflect isotope scarcity, production constraints, regulatory compliance, and differentiated product quality.
• Partner with Finance and Operations to assess deal economics, risk exposure, and downstream execution implications before commitments are made.
• Own pipeline governance: ensure forecasting accuracy, scenario planning, and clear articulation of upside, downside, and execution risk.
• Prepare executive-level materials and recommendations for leadership decision-making, including deal approvals, prioritization conflicts, and investment trade-offs.

Cross-Functional Leadership & Enterprise Execution:

• Act as the commercial integrator across Technical Operations, Quality, Regulatory, Supply Chain, Finance, and Program Management.
• Drive disciplined customer onboarding and internal handoffs, ensuring commercial commitments align with operational reality.
• Lead difficult conversations when scope, timing, or feasibility must be renegotiated—internally or externally.
• Elevate the voice of the customer while maintaining strong stewardship of safety, quality, and compliance standards.
• Influence enterprise priorities by articulating market demand signals, customer risk, and growth opportunities to executive leadership.

Portfolio Strategy & Capability Development:

• Partner with executive leadership to evaluate new capabilities, service lines, and infrastructure investments.
• Build business cases incorporating market demand, competitive differentiation, capital requirements, operational complexity, and return expectations.
• Guide decisions on build vs. partner vs. defer strategies for new capabilities.
• Ensure new offerings are commercially viable, operationally executable, and clearly differentiated in the market.

Leadership, Talent Development & Succession Readiness:

• Demonstrate enterprise-level leadership presence, judgment, and credibility with senior executives, Board-level discussions, and external partners.
• Mentor and develop commercial talent; contribute to building scalable commercial processes and leadership bench strength.
• Serve as a role model for disciplined thinking, accountability, and ethical decision-making in a regulated environment.
• Develop capabilities that position the role to take on broader commercial responsibilities as the organization evolves.

Qualifications

Minimum Education/Experience Requirements:

• Bachelor’s degree in Business, Life Sciences, Engineering, or a related discipline.
• Minimum twelve (12) years of progressive experience in business development / sales / strategic accounts within pharmaceutical, biotech, CDMO/CMO, radiopharmaceuticals, nuclear medicine, sterile manufacturing, or adjacent advanced therapeutic sectors.
• Demonstrated success closing complex, consultative deals with cross-functional execution (Quality, Technical Ops, Supply Chain, Legal, Finance).
• Strong command of pipeline management, forecasting, and CRM discipline.
• Demonstrated ability to lead through ambiguity in early-stage or rapidly scaling organizations.
• Proven experience making strategic trade-offs between growth, risk, margin, and capacity.
• Executive-level communication skills, including the ability to influence without authority and present to senior leadership and Boards.
• Strong financial acumen, including pricing strategy, margin analysis, and investment evaluation.

Preferred Education/Experience:

• Advanced degree (MBA, MS, PhD) in business or life sciences.
• Experience with one or more of the following:
• Radiopharmaceuticals / radioisotopes / nuclear pharmacy ecosystem.
• Regulated manufacturing environments (GMP), tech transfer, scale-up, or lifecycle program expansion.
• Clinical supply, cold chain/logistics, or time-sensitive distribution models

Please note the company cannot provide immigration-related sponsorship (including H-1B status, O-1 status, Optional Practical Training support, etc.) for this position.  Each successful applicant will be required to complete the Form I-9, Employment Eligibility Verification, demonstrating both identity and employment authorization, on or before the first day of employment.  Under federal law, only truthful information may be provided on the Form I-9.

Location

NorthStar Medical Radioisotopes is proud to call Beloit, Wisconsin home. Our headquarters and primary manufacturing facility are located in this vibrant, growing community that combines the charm of a small city with the advantages of a central Midwest location. Beloit features a lively, revitalized downtown filled with local restaurants, shops, and cultural events, and is just a short drive from major metropolitan areas including Madison, Milwaukee, Chicago, and Rockford.

Situated in the heart of the South Central Wisconsin and Northern Illinois region, Beloit offers a rare blend of urban amenities and scenic natural surroundings. Whether you’re drawn to outdoor recreation, educational institutions, the arts, or historic landmarks, the area provides rich and diverse experiences for all interests. A variety of nearby communities, ranging from rural towns to suburban neighborhoods, offer flexible housing options and access to multiple school districts, making Beloit an excellent choice for individuals and families considering relocation.

NorthStar Medical Radioisotopes is an equal opportunity employer. Employment decisions are made without regard to race, color, religion, national or ethnic origin, sex, sexual orientation, gender identity or expression, age, disability, protected veteran status or other characteristics protected by law.