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Senior Scientist, MRD

NeoGenomics Laboratories
Aliso Viejo, CA Full Time
POSTED ON 1/9/2026
AVAILABLE BEFORE 3/9/2026
Are you motivated to participate in a dynamic, multi-tasking environment? Do you want to join a company that invests in its employees? Are you seeking a position where you can use your skills while continuing to be challenged and learn? Then we encourage you to dive deeper into this opportunity. We believe in career development and empowering our employees. Not only do we provide career coaches internally, but we offer many training opportunities to expand your knowledge base! We have highly competitive benefits with a variety HMO and PPO options. We have company 401k match along with an Employee Stock Purchase Program. We have tuition reimbursement, leadership development, and even start employees off with 16 days of paid time off plus holidays. We offer wellness courses and have highly engaged employee resource groups. Come join the Neo team and be part of our amazing World Class Culture! NeoGenomics is looking for a Senior Scientist who wants to learn to continue to learn in order to allow our company to grow. This is an onsite position working out of the Aliso Viejo, CA laboratory with a Monday - Friday day shift.  Now that you know what we're looking for in talent, let us tell you why you'd want to work at NeoGenomics: As an employer, we promise to provide you with a purpose driven mission in which you have the opportunity to save lives by improving patient care through the exceptional work you perform. Together, we will become the world's leading cancer reference laboratory. Position Summary:  As a Senior Scientist you will provide technical leadership in developing next-generation sequencing clinical diagnostic assays for cancer patients. You will have the chance to apply your knowledge and background in clinical NGS assay development. You will lead the hands-on development process throughout the stages of feasibility, validation, regulatory submissions, and iterative improvements is a must-have. Responsibilities:
  • Be a driver for novel MRD assay throughout development phases.
  • Independently designs and executes complex NGS experiments.
  • Be proactive, creative, and pragmatic in analyzing and discussing NGS data.
  • Performs the literature review, participates in creating project proposals and product requirements with stakeholders.
  • Analyzes results, presents data, and updates the management team on projects.
  • Provides support to research collaborations, clinical trials, and other department projects.
  • Prepares high-quality technical reports (including validation, verification, and final project) and documentation, including posters/papers, client presentations, and technical content for marketing materials.
Education, Experience & Qualifications
  • Ph.D. in cancer genomics or related fields preferred; M.S. with related experience will be considered
  • Experience in developing assays for minimal residual disease (MRD) is highly desirable.
  • Five or more years of laboratory experience in developing NGS clinical diagnostic assays.
  • Strong preference for candidates with expertise in minimal residue disease detection in solid tumors.
  • Experience in following design control
  • Excellent skills in documentation for LDTs in CLIA/CAP environment.
  • Track record in assay development that achieved reimbursement and other external approvals.

Salary.com Estimation for Senior Scientist, MRD in Aliso Viejo, CA
$118,807 to $146,126
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