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Scientist | Engineer, Machine Learning | Bioinformatics

Moonwalk Biosciences
South San Francisco, CA Full Time
POSTED ON 7/6/2026
AVAILABLE BEFORE 8/1/2026

About Us:

Moonwalk Biosciences is pioneering therapeutics in adipose biology driven by deep genetic and epigenetic insights. Moonwalk’s discovery platform has resulted in novel adipose targets from deep genetic and epigenetic associations, advanced AI prediction tools, and profiling of primary human samples. Moonwalk is advancing a pipeline of multiple FIC targets addressing diverse adipose mechanisms and indications.


Moonwalk was Co-founded by Alex Aravanis, M.D., Ph.D., former CTO of Illumina, world-renowned scientist Feng Zhang, Ph.D. of the Broad Institute of MIT and Harvard, and a distinguished set of industry leaders and company builders. It has raised $57 million led by Alpha Wave Ventures, and joined by other leading life sciences investors ARCH Venture Partners, Future Ventures, GV, Khosla Ventures and YK Bioventures.


Position Overview:

Moonwalk Biosciences is recruiting a Senior Scientist/Engineer, Machine Learning / Bioinformatics to join our multidisciplinary R&D team. This individual will play a key role in advancing Moonwalk’s mission to develop first-in-class medicines through the discovery and functional characterization of novel therapeutic targets. As a core member of the computational biology group, you will work closely with experimental scientists and build machine learning systems to support target discovery and preclinical work.


Key Responsibilities:

  • Develop internal “AI co-scientist” tools, connecting LLMs to our proprietary and public datasets to help generate therapeutic hypotheses.
  • Work directly with experimental scientists to gather feedback on the tools and use it to guide ongoing development.
  • Write clean, maintainable Python code and document your methods clearly so pipelines are robust and reproducible for the broader team.


Required Qualifications:

  • Ph.D. in Computer Science, Bioinformatics, Computational Biology, or a related field (or M.S. with 3 years of relevant experience).
  • Strong software engineering fundamentals, including proficiency in Python.
  • A pragmatic mindset: you are motivated by the end goal of advancing therapeutics and enjoy building reliable, useful tools that directly advance our preclinical programs.
  • Excellent collaboration, communication, and problem-solving skills.
  • Track record of impactful contributions, including open-source tool development or peer-reviewed publications.


Preferred Skills and Experience:

  • Experience analyzing genomics or other preclinical biological data.
  • Familiarity working with LLM APIs, prompt engineering, or agentic workflows.


Equal Opportunity Employer:

Moonwalk Biosciences provides equal employment opportunities to all employees and applicants for employment and prohibits discrimination and harassment of any type without regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state or local laws.


This policy applies to all terms and conditions of employment, including recruiting, hiring, placement, promotion, termination, layoff, recall, transfer, leaves of absence, compensation and training.

Salary : $130,000 - $173,000

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