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Principal Project Engineer

MilliporeSigma
Jaffrey, NH Full Time
POSTED ON 4/8/2026
AVAILABLE BEFORE 5/6/2026
Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you’ve got big plans – so do we! Our colleagues across the globe love innovating with science and technology to enrich people’s lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

Your Role

As a Principal Project Engineer in the Engineering & Technology Team you are a critical business partner to ensure we will meet our ambitious investment objectives in our Life Science business unit. You will support the preparation and execution of large, strategic investment projects as a technical expert for process engineering. The projects are generally large (multi-million dollars) and/or of a complex nature. You will support the sites and business stakeholders in developing the technical project scope and ensure seamless implementation of the most efficient, viable technical solution in alignment with internal standards and any binding requirements. At the same time, you might have the opportunity to manage smaller projects from ideation to implementation. You will also contribute to the execution of the LS strategy and strive for technological advancement by fulfilling internal customer requirements with state-of-the-art and sustainable solutions, leveraging the internal technology network across the whole organization.

You will be supporting the North American region. The position will be located in or near Jaffrey, NH.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

There is 10% domestic and international travel required to meet business needs.

Key Responsibilities

Manage Equipment validation and qualification

    • Manage change control and re-validation to maintain ongoing compliance.
  • Equipment build, commissioning, and start-up
    • Influence equipment design inputs, vendor selection, and build for manufacturability and reliability.
    • Lead FAT/SAT, installation/commissioning, site acceptance testing, and handover to operations.
  • Project governance and planning
    • Develop and maintain WBS, schedules, milestones, and critical-path analyses.
    • Establish vendor evaluation criteria, due diligence, and gating processes.
  • Risk, safety, and compliance
    • Conduct hazard analyses, FMEA; ensure alignment with internal standards and regulatory requirements.
  • Documentation and communication
    • Create standardized templates for charters, business cases and risk registers
    • Provide clear, factual reporting to stakeholders and governance bodies.
Who You Are

Minimum Qualifications:

  • BS or MS in Process Engineering (considering BS or MS in Mechanical Engineering or Chemical Engineering with heavy focus in process engineering)
  • 8 years of professional experience in pharma or life science
  • Must have significant skills and experience in project management and ideally a history of successfully executed smaller technical investment projects (0.5M$-10M$) as project lead

Preferred Qualifications

  • PMP certification or ability to obtain it within 12 months
  • Fluent in English with excellent communication skills and have a profound knowledge of quality regulations
  • Ability to analyze situations and systems to develop or identify optimized solutions in line with project scope, time and cost
  • History of successfully implemented equipment or systems along the whole value chain from design, installation to start-up
  • Ability to work effectively, and have demonstrated documentation skills
  • Inclusive and can identify required resources, internal or external experts and stakeholders

Pay Range for this position: $116,700-$175,100

The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses. Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites. For more information click here.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of a team that is dedicated to Sparking Discovery and Elevating Humanity!

Salary : $116,700 - $175,100

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