What are the responsibilities and job description for the Principal Investigator position at Metric Bio?
Principal Investigator – Clinical Research
Hours: Full-time, Monday–Friday, 8:00 AM – 2:30/4:30 PM
Salary: $250,000 – $300,000 base full benefits package
Company: Metric Search, partnered with a leading Clinical Research Organisation
About the Role
Metric Search is proud to partner with a leading, multi-site Clinical Research Organisation operating across a network of 18 clinical research sites. We are seeking a Principal Investigator to join one of their established research centres, contributing to industry-leading clinical trials and advancing medical innovation.
This is a full-time, on-site role with prior experience serving as a Principal Investigator (or extensive Sub-Investigator experience).
Key Responsibilities
- Serve as the Principal Investigator for assigned clinical trials, ensuring all studies are conducted in accordance with ICH-GCP and regulatory requirements.
- Collaborate with study sponsors and CRO teams - acting as the site’s subject matter expert (SME) in your field.
- Provide medical oversight for study participants, including in-house or virtual patient calls during business hours.
- Rotate after-hours call duties with two other investigators (no after-hours phone coverage required individually).
- Participate in investigator meetings, sponsor calls, and industry conferences.
- Support site operations and patient recruitment during both high- and low-enrolment seasons.
Ideal Candidate
- Board-certified.
- US Medical License.
- Experience as a Principal Investigator preferred; Sub-Investigator experience in Pfizer-sponsored or major pharmaceutical trials will be strongly considered.
- Committed to full-time site involvement (no multiple practice commitments).
- Passionate about clinical research and patient-centred science.
- Strong communicator with a collaborative, leadership-oriented approach.
What’s on Offer
- Competitive base salary of $250,000 – $300,000
- Relocation support provided
- Opportunity to work within a network of 18 sites
- Regular exposure to sponsors, industry leaders, and conferences
If this sounds like your next step, please apply, or contact executive search consultant - Oli Oldham on oli.oldham@metric-search.com.
Salary : $250,000 - $300,000
