What are the responsibilities and job description for the Senior Principal Scientist, Outcomes Research position at Merck?
Job Description
In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company’s renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health.
The Senior Principal Scientist leads a team of health economists to develop and implement health economics and modeling strategies that enable the Company to understand and communicate the full economic value of the Company’s oncology products to payers, health technology agencies, policy makers, and other decision-makers in order to optimize market access and patient outcomes.
Main Responsibilities
Under the direction of an Executive Director within the Health Economic and Decision Sciences (HEDS) department of the BARDS) organization, the Senior Principal Scientist will:
Education
#eligibleforERP
Required Skills
Commercialization, Data Management, Decision Models, Healthcare Technology, Health Economics, Market Access, Mathematics, Medical Economics, Mentorship, Prioritization, Product Development, Researching, Stakeholder Relationship Management, Strategic Planning, Strategic Planning Partnerships, Strategic Thinking
Preferred Skills
Current Employees apply HERE
Current Contingent Workers apply HERE
US And Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
Requirements
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
The salary range for this role is
$210,400.00 - $331,100.00
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status
Regular
Relocation:
No relocation
VISA Sponsorship
No
Travel Requirements
10%
Flexible Work Arrangements
Hybrid
Shift
Not Indicated
Valid Driving License
No
Hazardous Material(s)
n/a
Job Posting End Date
06/11/2026
In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company’s renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health.
The Senior Principal Scientist leads a team of health economists to develop and implement health economics and modeling strategies that enable the Company to understand and communicate the full economic value of the Company’s oncology products to payers, health technology agencies, policy makers, and other decision-makers in order to optimize market access and patient outcomes.
Main Responsibilities
Under the direction of an Executive Director within the Health Economic and Decision Sciences (HEDS) department of the BARDS) organization, the Senior Principal Scientist will:
- Lead a team in the development and execution of health economic and modeling strategies to support the value of the Company’s oncology portfolio
- Provide leadership, mentorship, and strategic direction to a team of 3–4 health economists
- Oversee the prioritization and development of high-quality global health economic models and tools to support market access, pricing, reimbursement, HTA submissions, and formulary decision-making across U.S. and international markets
- Collaborate with key countries and the regional team to adapt global models for local HTA, reimbursement, and formulary submissions
- Generate and communicate early health economic insights to inform development and commercialization strategies
- Build strong partnerships with internal stakeholders to ensure modeling strategies align and support the overall product development and value evidence strategy and implementation
- Develop and maintain relationships with external thought leaders in health economics, decision sciences, and health policy to enhance scientific credibility, inform strategy, and position our company as a leader in the field
Education
- PhD (preferred) in Quantitative Sciences such as Health Economics, Mathematics, Predictive Modeling, Statistics, Operations Research, Physics, Engineering or closely related field with 7 or more years of relevant experience; or
- Master’s degree with at least 9 years of relevant work experience
- Demonstrated ability to lead and manage teams
- Excellent written and verbal communication skills
- Strong strategic thinking and problem-solving skills
- Ability to work independently and interact effectively with a broad group of stakeholders
- Ability to manage multiple priorities and deadlines
- Ability to translate complex analyses into actionable insights
- Experience in developing health economic models for decision-making
- Strong expertise in oncology modeling
- Experience with HTA and reimbursement submissions
#eligibleforERP
Required Skills
Commercialization, Data Management, Decision Models, Healthcare Technology, Health Economics, Market Access, Mathematics, Medical Economics, Mentorship, Prioritization, Product Development, Researching, Stakeholder Relationship Management, Strategic Planning, Strategic Planning Partnerships, Strategic Thinking
Preferred Skills
Current Employees apply HERE
Current Contingent Workers apply HERE
US And Puerto Rico Residents Only
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.
Requirements
As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit:
EEOC Know Your Rights
EEOC GINA Supplement
We are proud to be a company that embraces the value of bringing together, talented, and committed people with diverse experiences, perspectives, skills and backgrounds. The fastest way to breakthrough innovation is when people with diverse ideas, broad experiences, backgrounds, and skills come together in an inclusive environment. We encourage our colleagues to respectfully challenge one another’s thinking and approach problems collectively.
Learn more about your rights, including under California, Colorado and other US State Acts
The salary range for this role is
$210,400.00 - $331,100.00
This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee’s position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.
The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.
We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.
You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.
San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance
Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles’ Fair Chance Initiative for Hiring Ordinance
Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.
Employee Status
Regular
Relocation:
No relocation
VISA Sponsorship
No
Travel Requirements
10%
Flexible Work Arrangements
Hybrid
Shift
Not Indicated
Valid Driving License
No
Hazardous Material(s)
n/a
Job Posting End Date
06/11/2026
- A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.
Salary : $210,400 - $331,100