Demo

Upstream Process Development Engineer/Scientist - REMOTE in California

Merck KgaA
Burlington, MA Remote Full Time
POSTED ON 4/27/2025
AVAILABLE BEFORE 6/27/2025

Job Details

Work Your Magic with us! Start your next chapter and join MilliporeSigma.

Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

MilliporeSigma is seeking an Upstream Process Development Scientist (PDS) - Field Based Remote / California to join the Technical and Scientific Solutions Team to support our West Coast customer sites. This role is part of a worldwide team of engineers and scientists, supporting and collaborating with customers in their use of MilliporeSigma's technologies. The ideal candidate is a scientist/engineer with industry experience, having a strong background in upstream bioprocess unit operations, particularly fed-batch and perfusion applications.

  • This is a California/West Coast-based position, with regular travel (40%) to internal and Western-US customer sites primarily in Bay area and San Diego.
  • Act as a technical partner to our end users, providing proactive technical collaboration and best practices guidance for MilliporeSigma's upstream product portfolio, along with technical recommendations for process development, optimization, scale-up and implementation of upstream applications.
  • Assess the feasibility and soundness of proposed upstream technical applications through experimental, material, and/or consultative support of upstream process development activities.
  • Support perfusion, bioreactor, and process analytical tools (PAT) technologies from initial screenings to late stage implementations, with a responsibility to independently design, direct and review experiments to understand process sensitivity/limitations, while critically analyzing data to troubleshoot application and operational issues.
  • Collaborate with our commercial team, R&D, and marketing teams to provide the voice of customers, market trends, thought leadership, and alignment of go-to-market strategies.
  • Interact with local and global colleagues to ensure a common "Best Practices" technical approach for upstream application development and implementation and drive continuous improvement in both tools and methodologies.
  • Report on all field activities in CRM software and other internal project databases.
  • Perform any additional tasks as assigned by your manager.

Who you are:

Minimum Qualifications:
  • Bachelor's Degree in in a life science discipline (e.g., Pharmaceutical Sciences, Chemistry or Biology, etc.) with 5 years of industry related upstream biopharmaceutical development experience

OR
  • Master's Degree or PhD in in a life science discipline (e.g., Pharmaceutical Sciences, Chemistry or Biology, etc.) with 3 years of industry related upstream biopharmaceutical development experience

Preferred Qualifications:
  • Strong background and hands-on experience in upstream processing of biotherapeutics (monoclonal antibodies and vaccines, cell and viral gene therapies experience).
  • In-depth knowledge of the development, scale up and implementation of upstream applications and technologies, including technologies for intensified processing and process analytics (cGMP experience is a plus).
  • Experience in intensified processing and process analytical tools.
  • Demonstration of solid data analysis and troubleshooting skills.
  • Strong project and time management skills.
  • Proven demonstration of proactive, independent project planning and execution
  • Experience working in matrixed global organization.
  • Well-developed verbal, listening and written communication skills, and the ability to respond to customer needs with urgency.
  • Understanding of mechanical, electronic, and pneumatic systems as well as computer hardware and software.
  • Experience with operating software and hardware from multiple vendors for upstream monitoring and control.
  • Experience in any relevant Millipore Sigma equipment.

Pay Range for this position - $78,000k - 123,600k

Our ranges are derived from several sources, and largely reliant on relevant industry market data. Should we decide to make an offer, we will consider several factors, including but not limited to your location, skills, experience, career level, and other job-related factors. This role may offer the following benefits: medical, vision, and dental insurance; life insurance; disability insurance; a 401(k) matching program; paid time off; and paid holidays; among other employee benefits. This role may also be eligible for short-term or long-term incentive compensation, including, but not limited to, cash bonuses.

What we offer: We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We celebrate all dimensions of diversity and believe that it drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

Apply now and become a part of our diverse team!

If you would like to know more about what diversity, equity, and inclusion means to us, please visit
Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.

Salary : $78,000 - $123,600

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