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Senior Medical Director - Neurodegeneration

Meet Life Sciences
Cambridge, MA Contractor
POSTED ON 5/8/2026
AVAILABLE BEFORE 6/5/2026

Senior Medical Director, Clinical Research – Neurodegeneration

Overview

We are seeking a physician leader to drive clinical development programs in neurodegeneration, with a primary focus on Huntington’s disease. This role will provide strategic and operational leadership across all stages of development, advancing innovative therapeutics from early research through late-stage clinical trials.

Key Responsibilities

  • Serve as the clinical lead for neurodegeneration programs, shaping and executing development strategy
  • Lead Phase 2/3 clinical trials, including study design, oversight, and safety monitoring
  • Partner cross-functionally with Regulatory, Clinical Operations, Biostatistics, Preclinical, Medical Affairs, and Commercial teams
  • Provide clinical guidance to research teams on target feasibility and early-stage development plans
  • Drive timelines, deliverables, and overall program execution
  • Oversee and contribute to key documents (protocols, IBs, regulatory submissions, publications, and presentations)
  • Represent clinical programs in regulatory interactions and scientific forums
  • Collaborate with external experts, investigators, and partners

Qualifications

  • MD or MD/PhD with a strong research background and publication record
  • 10 years of industry or equivalent academic clinical development experience
  • Proven success leading Phase 2/3 clinical programs and engaging with regulatory authorities
  • Experience in neurology or neurodegenerative diseases (Huntington’s disease preferred)
  • Strong knowledge of clinical trial design, biostatistics, and regulatory frameworks
  • Excellent leadership, communication, and stakeholder management skills
  • Ability to operate effectively in a fast-paced, matrixed environment

Location

Hybrid work environment with flexibility based on business needs.

Hourly Wage Estimation for Senior Medical Director - Neurodegeneration in Cambridge, MA
$118.00 to $150.00
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