Demo

Lead Threat Detection Engineer

McKesson Corporation
Irving, TX Full Time
POSTED ON 5/17/2026 CLOSED ON 6/17/2026

What are the responsibilities and job description for the Lead Threat Detection Engineer position at McKesson Corporation?

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve - we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow's health today, we want to hear from you.

McKesson's Lead Threat Detection Engineer will be a member of our global cyber threat intelligence, incident response, analytics, and engineering team responsible for advancing our detection capabilities and tools. This team is responsible for building detection content, enabling integration, automation, enrichment, and performance of alerts. This role enables speed, quality, and coverage of threats for security operations and reduces risk to McKesson business operations.

Position Description/Responsibilities

  • Mature from a manual detection practice to a modern, automated, and standardized Detection-as-Code practice and infrastructure.
  • Develop use-cases based on intelligence, red team results, and incident data
  • Develop IOC workflows and a feedback loop for the Threat Intel Platform (TIP)
  • Write detection and correlation rules to identify threats across our stack
  • Assist in onboarding logs and identifying gaps in logs or alert results
  • Develop a deep understanding of data models, macros, indexes, sources, and field alias and the technology foundation our detection stack is built
  • Understand data schema/API standards, automation, and messaging systems
  • Bring a metrics-driven mindset to our rules, signals (IOCs), and alerts

Critical Requirements

  • Prioritize detection use-case and scope and create a logical rule
  • Ability to prioritize decisions to either write a rule and/or tune a tool/policy
  • Practical experience with threat Actor tracking, tactics, tools, and techniques and working closely with Intel, SOC, and Red Teams (Purple Teams)
  • Ability to measure detection coverage across common frameworks (e.g. NIST CSF, MITRE, KC) and simplify rules and configurations to optimize alerts
  • Ability to automate tasks via scripting, automating inputs and outputs of APIs, and programming skills such as python to enable detection engineering tasks
  • Exceptional interpersonal, organizational, and communication skills and ability to internalize and exemplify Mckesson core values.
  • Splunk SPL knowledge and SIEM experience or additional SIEM background

Following Qualifications would be advantageous:

  • 10 years of professional experience in two or more domains, including: detection engineering, data engineering, incident response, threat hunting, threat intelligence.
  • Bachelor's degree in computer science, Information Security, Security Engineering, Statistics, or Data Science
  • Chronicle Experience, Splunk Certifications (1,2), Automation certifications (Security with Python SEC573), Sigma Rules

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, pleaseclick here.

Our Base Pay Range for this position

$139,000 - $231,600

McKesson is an Equal Opportunity Employer

McKesson provides equal employment opportunities to applicants and employees and is committed to a diverse and inclusive environment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability, age or genetic information. For additional information on McKesson's full Equal Employment Opportunity policies, visit our Equal Employment Opportunity page.

Join us at McKesson!


McKesson is an equal opportunity and affirmative action employer - minorities/females/veterans/persons with disabilities.

 

Salary.com Estimation for Lead Threat Detection Engineer in Irving, TX
$125,623 to $154,763
If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Lead Threat Detection Engineer?

Sign up to receive alerts about other jobs on the Lead Threat Detection Engineer career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$99,793 - $130,112
Income Estimation: 
$125,027 - $157,872
Income Estimation: 
$162,237 - $199,353
Income Estimation: 
$222,110 - $256,974
Income Estimation: 
$224,976 - $270,947
Income Estimation: 
$205,834 - $254,869
Income Estimation: 
$242,530 - $287,120
This job has expired.
Employees: Get a Salary Increase
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at McKesson Corporation

  • McKesson Corporation Fallon, MT
  • McKesson is an impact- driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and se... more
  • Just Posted

  • McKesson Corporation Overland Park, KS
  • McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and ser... more
  • Just Posted

  • McKesson Corporation Fairfield, NJ
  • Our McKesson location in Fairfield, NJ is looking for a dynamic and motivated driver associate to join the team. This is a fantastic chance to work for a c... more
  • Just Posted

  • McKesson Corporation Alpharetta, GA
  • McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and ser... more
  • Just Posted


Not the job you're looking for? Here are some other Lead Threat Detection Engineer jobs in the Irving, TX area that may be a better fit.

  • TrendAI Irving, TX
  • Trend Micro, a global cybersecurity leader, helps make the world safe for exchanging digital information across enterprises, governments, and consumers. Fu... more
  • 2 Days Ago

  • Vanguard Group, Inc. Dallas, TX
  • The AI Threat Detection Engineer, Senior Specialist is responsible for developing and implementing AI-driven capabilities that enhance Security Operations ... more
  • 1 Day Ago

AI Assistant is available now!

Feel free to start your new journey!