Demo

Manager, Quality Engineering – Validation

McGuff Companies
Santa Ana, CA Full Time
POSTED ON 5/14/2026
AVAILABLE BEFORE 11/9/2026

About McGuff Pharmaceuticals, Inc.

For more than two decades, McGuff Pharmaceuticals, Inc. (McGuff) has been a trusted leader in sterile pharmaceutical manufacturing. We are an FDA-registered commercial drug manufacturer and FDA 503B outsourcing facility known for our integrity, precision, and innovation.


As a family- and veteran-owned organization, McGuff Medical is committed to excellence in every aspect of sterile production — from concept to patient care.


We are seeking a strong, motivational leader to manage our Quality Engineering – Validation (QEV) team and drive a culture of scientific rigor, operational excellence, and continuous improvement.


If you are a hands-on technical leader with a passion for compliance, data-driven decision-making, and developing exceptional people — this is your opportunity to make a lasting impact.


What You’ll Do

• Lead and inspire a team of validation engineers to ensure all systems, utilities, and manufacturing processes remain in a validated state.

• Build and reinforce a culture of excellence, collaboration, and accountability within the Quality Unit (QU).

• Oversee and approve the development and execution of IQ/OQ/PQ, process validation, and cleaning validation protocols.

• Apply statistical analysis and data-driven decision-making to monitor process performance and product consistency.

• Lead complex investigations, applying structured root cause analysis and driving CAPA implementation with measurable, sustainable results.

• Own and continuously enhance the Validation Master Plan (VMP) and validation lifecycle management systems.

• Represent McGuff during FDA inspections, customer audits, and quality reviews.

• Collaborate cross-functionally with Engineering, Manufacturing, and QA to optimize systems, processes, and inspection readiness at all times.


Who You Are

• A true leader — you mentor, motivate, and elevate others while setting uncompromising quality standards.

• A leader committed to training employees 

• A strategic thinker capable of connecting long-term vision with practical implementation.

• A data-driven problem solver who uses science, logic, and disciplined analysis to drive continuous improvement.

• Comfortable leading in a regulated sterile manufacturing environment and communicating effectively with regulatory agencies.


What You Bring

• A Bachelor’s or Master’s degree in Engineering, Life Sciences, or a related technical discipline.

• 10 years of experience in pharmaceutical or medical device validation, including 5 years in a leadership role.

• Hands-on expertise in aseptic process validation, equipment qualification, and computerized system validation (CSV).

• Strong command of statistical tools, process capability analysis, and trending methodologies.

• Proven proficiency in root cause analysis and CAPA management.

• In-depth knowledge of FDA, ICH, and EU GMP regulatory standards.

• Excellent communication, documentation, and presentation skills.


Why McGuff

• Stable, family- and veteran-owned company with over 20 years of proven success in sterile manufacturing.

• Leadership opportunity with clear potential for advancement and influence.

• Work directly with senior management in an organization that truly values quality above all else.

• Competitive compensation, comprehensive benefits, and a positive, mission-driven culture.


📧 Apply Now: employment.mpi@mcguff.com


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