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Manager, SOX Compliance

MBX Biosciences, Inc.
Carmel, IN Full Time
POSTED ON 6/5/2026
AVAILABLE BEFORE 7/4/2026
Position Summary

We are seeking a Manager, SOX Compliance and Accounting, specializing in Sarbanes Oxley (SOX) compliance and project accounting, to join our finance and accounting team. Reporting to the Assistant Controller, this individual will be responsible for overseeing the initial buildout, ongoing maintenance and testing of the Company’s SOX compliance program in anticipation of SOX 404b compliance requirements, as well as accurate and timely preparation of monthly project accounting and other month-end accounting responsibilities as needed. This role requires strong leadership skills, extensive knowledge of SOX compliance, US GAAP, COSO internal control frameworks and the ability to manage complex accounting processes. Communication, organizational skills, and attention to detail, as well as the ability to multi-task, are key to successful incumbents consistently functioning at the highest level with the utmost regard for the MBX’s mission & values.

Key Responsibilities

Including but not limited to:

  • Manage the buildout of the Company’s SOX Compliance program, including the identification of entity-level controls, process-level controls, and ITGCs.
  • Conduct ongoing risk and control assessments by identifying financial reporting risks, evaluating entity-level and process-level controls, and assessing IT general and application controls.
  • Lead internal controls walkthroughs and testing.
  • Maintain and improve SOX documentation, including risk control matrices, process flows and test procedures.
  • Assist with managing and coordinating the external Audit team as it relates to SOX Compliance.
  • Recommend and implement changes to strengthen internal controls and financial processes, as needed.
  • Assist with major project accounting percentage of completion entries and standardization of related processes.
  • Assist accounting functions and month-end closing, ensuring GAAP compliance, internal controls and timely completion of procedures.
  • Audit Coordination: Assist with the preparation and coordination of internal and external annual audits and quarterly reviews.
  • Provide accounting support for special projects and ad-hoc reporting and analysis, as necessary.
  • Maintains direct, open, and constant communication with functional department leads to relay important information in a timely manner.

Education & Qualifications

  • Degree in Finance or Accounting; Masters or MBA a plus, but not required.
  • Corporate accounting experience in life sciences industry or CPA with audit experience (life science clients a plus) is required.
  • Technical knowledge in US GAAP and COSO framework.

Experience & Additional Skills

  • 3 years in financial reporting, audit or accounting.
  • 2 years of SOX, internal controls, or audit experience.
  • Internal Controls: Design and maintain internal controls and SOX.
  • Clear and concise documentation skills and proven ability coordinate with auditors and process owners.
  • Ability to oversee, or assist with overseeing of, month-end accounting processes.
  • Assist with SEC Filings preparation, as needed: (Forms 10-Q, 10-K, 8-K, 3, 4, proxy statements, earnings releases) ensuring US GAAP and SEC compliance.
  • Proficiency in Microsoft Office Suite; experience with ActiveDisclosure and NetSuite ERP is a plus.

Travel

You will be expected to travel periodically based on the needs of the business to the extent requested by the Company, including attendance at Together Weeks, Together Days, and functional meetings as requested by the Company.

Company Overview

MBX Biosciences is a biopharmaceutical company focused on the discovery, development and commercialization of novel precision peptide therapies based on its proprietary PEP™ platform, for the treatment of endocrine and metabolic disorders. The Company is advancing a pipeline of novel candidates for endocrine and metabolic disorders with clinically validated targets, established endpoints for regulatory approval, significant unmet medical needs and large potential market opportunities. The Company’s pipeline includes canvuparatide (MBX 2109) for the treatment of chronic hypoparathyroidism preparing for Phase 3 development; and an obesity portfolio that includes MBX 4291 in Phase 1 development and MBX 5765 in preclinical development, as well as additional discovery candidates. The Company is based in Carmel, Indiana and Burlington, Massachusetts. To learn more, please visit the Company website at www.mbxbio.com and follow it on LinkedIn.

EEO Statement

MBX Biosciences is an Equal Opportunity Employer and is committed to treating all applicants fairly without discrimination. We welcome applications from all individuals, regardless of race, national origin, gender, age, physical characteristics, social origin, disability, union membership, religion, family status, pregnancy, sexual orientation, gender identity, gender expression or any unlawful criterion under applicable law.

Salary.com Estimation for Manager, SOX Compliance in Carmel, IN
$113,806 to $143,750
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