What are the responsibilities and job description for the Senior Biostatistician position at Mass General Brigham?
Site: The General Hospital Corporation
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Massachusetts General Hospital (MGH) is the largest research hospital in the United States with an annual research budget of over one billion dollars. The Neurological Clinical Research Institute (NCRI) at MGH was formed in 1994 by Dr. Merit Cudkowicz to help foster clinical research in the Department of Neurology and conduct clinical research in neurological disorders. Under the direction of Drs. James Berry, Sabrina Paganoni, and Suma Babu, NCRI functions as a Clinical and Data Coordination Center for research studies and therapeutic trials, including the HEALEY ALS Platform Trial and the MyMatch Trial. NCRI also serves as the Coordination Center for the Network of Excellent in ALS (NEALS) consortium and the NeuroNEXT network. Research at NCRI is supported by a Biostatistics group that includes multiple faculty statisticians, an operational director, and staff biostatisticians and statistical programmers. The group is supplemented by close collaborations with MGH Biostatistics and with colleagues at the Departments of Biostatistics and Epidemiology at the TH Chan School of Public Health at Harvard University.
MGH NCRI is seeking qualified applicants with master’s degrees in Biostatistics or a related field to serve as a Senior Biostatistician within the NCRI Biostatistics group. This is a unique role for a biostatistician who enjoys hands-on, cross-disciplinary work in a mission-driven setting. The position offers the chance to shape the design, conduct, and analysis of important research while working with a diverse team across academia, industry, and regulatory bodies. While housed within a renowned academic institution, the position offers the fast-paced, solution-oriented environment of industry and is ideal for a candidate who thrives on meaningful real-world applications.
Job Purpose
The Senior Biostatistician will be responsible for assisting statistical operations, including design, analysis, validation, and reporting of data to support clinical research and investigational product development. The individual will work closely with faculty biostatisticians and clinical investigators on a variety of projects focused on neurodegenerative diseases including academic and FDA-regulated clinical trials, observational studies, and registries. The individual will ensure the application of rigorous statistical methods and error-free statistical programming (using SAS and R) to produce accurate, reliable, and reproducible results. The individual will be expected to work closely with other team members to achieve larger goals while also taking ownership of projects and tasks and independently identifying areas that require additional attention or improvement in both their own and the team’s work.
Prinicipal Duties And Responsibilities
Applicants should meet the following qualifications:
Master's Degree
Field Of Study/Additional Specialized Training
Biostatistics, Statistics, Epidemiology, Computer Science, Mathematics, Engineering, Life Science, or related field
Working Conditions
This position is typically a hybrid of in-person and remote work. Fully remote work may be negotiable with the supervisor. Hybrid and remote positions must have reliable access to the internet. Regardless of typical work location, on occasion and at the discretion of the NCRI Director of Quality Assurance, the Senior Biostatistician may be required to be onsite at MGH for meetings, sponsor audits, or regulatory inspections. Advanced notice will be given. Periodic in-person attendance will be required at the discretion of supervisor.
Summary
Job Summary
Responsible for collecting data from medical research and analyzing it to draw conclusions or make predictions. Also responsible for developing and executing research studies in collaboration with other statisticians and scientists, monitoring clinical trials to ensure the integrity of the results.
Does this position require Patient Care?
No
Essential Functions
Education
Master's Degree Statistics required or Master's Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Experience
Advanced Statistics/Biostatistics Experience 3-5 years required
Knowledge, Skills And Abilities
Additional Job Details (if applicable)
Hybrid
Work Location
399 Revolution Drive
Scheduled Weekly Hours
40
Employee Type
Regular
Work Shift
Day (United States of America)
Pay Range
$93,953.60 - $136,739.20/Annual
Grade
7
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement
1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Massachusetts General Hospital (MGH) is the largest research hospital in the United States with an annual research budget of over one billion dollars. The Neurological Clinical Research Institute (NCRI) at MGH was formed in 1994 by Dr. Merit Cudkowicz to help foster clinical research in the Department of Neurology and conduct clinical research in neurological disorders. Under the direction of Drs. James Berry, Sabrina Paganoni, and Suma Babu, NCRI functions as a Clinical and Data Coordination Center for research studies and therapeutic trials, including the HEALEY ALS Platform Trial and the MyMatch Trial. NCRI also serves as the Coordination Center for the Network of Excellent in ALS (NEALS) consortium and the NeuroNEXT network. Research at NCRI is supported by a Biostatistics group that includes multiple faculty statisticians, an operational director, and staff biostatisticians and statistical programmers. The group is supplemented by close collaborations with MGH Biostatistics and with colleagues at the Departments of Biostatistics and Epidemiology at the TH Chan School of Public Health at Harvard University.
MGH NCRI is seeking qualified applicants with master’s degrees in Biostatistics or a related field to serve as a Senior Biostatistician within the NCRI Biostatistics group. This is a unique role for a biostatistician who enjoys hands-on, cross-disciplinary work in a mission-driven setting. The position offers the chance to shape the design, conduct, and analysis of important research while working with a diverse team across academia, industry, and regulatory bodies. While housed within a renowned academic institution, the position offers the fast-paced, solution-oriented environment of industry and is ideal for a candidate who thrives on meaningful real-world applications.
Job Purpose
The Senior Biostatistician will be responsible for assisting statistical operations, including design, analysis, validation, and reporting of data to support clinical research and investigational product development. The individual will work closely with faculty biostatisticians and clinical investigators on a variety of projects focused on neurodegenerative diseases including academic and FDA-regulated clinical trials, observational studies, and registries. The individual will ensure the application of rigorous statistical methods and error-free statistical programming (using SAS and R) to produce accurate, reliable, and reproducible results. The individual will be expected to work closely with other team members to achieve larger goals while also taking ownership of projects and tasks and independently identifying areas that require additional attention or improvement in both their own and the team’s work.
Prinicipal Duties And Responsibilities
- Develop statistical analysis plans for clinical trials, observational studies, and other biomedical research projects
- Conduct statistical analyses for clinical trials, observational studies, and registry data, including analyses of longitudinal outcomes, survival data, and other complex study designs using appropriate statistical models (e.g., mixed-effects models, survival models); begin to oversee biostatisticians and/or statistical programmers
- Generate reports of study progress, including reports for data and safety monitoring boards, and assist in the design of these reports
- Develop programs and guide efforts to perform robust data manipulation and error detection to ensure data integrity
- Assist in power calculations, determine sample size requirements, and advise on experimental design
- Assist and contribute to statistical analyses for scientific manuscripts, including drafting statistical methods sections, preparing tables and figures, and collaborating with investigators on interpretation and presentation of results
- Assist in the design of clinical studies and review protocols for statistical considerations
- Provide statistical guidance for grants and other funding proposals
- Engage in professional development opportunities
Applicants should meet the following qualifications:
- Masters (MS/MA) in Biostatistics, Statistics, Epidemiology, Computer Science, Mathematics, Engineering, Life Science, or related field.
- 3 years of professional experience in academic medicine or pharmaceutical industry setting.
- Proficiency with SAS or R.
- Experience supporting studies in all phases from design through publication.
- Ability to explain statistical concepts to non-statistical collaborators.
- Exceptional attention to detail and organizational skills.
- Strong ability to identify and resolve issues, manage competing priorities, and meet timelines consistently.
- Self-motivated with a commitment to producing high quality, on-time deliverables and a strong sense of ownership.
- Excellent written and verbal communication skills, with the ability to effectively collaborate with multidisciplinary teams.
- Team-oriented mindset with a commitment to fostering collaboration and building productive working relationships.
Master's Degree
Field Of Study/Additional Specialized Training
Biostatistics, Statistics, Epidemiology, Computer Science, Mathematics, Engineering, Life Science, or related field
Working Conditions
This position is typically a hybrid of in-person and remote work. Fully remote work may be negotiable with the supervisor. Hybrid and remote positions must have reliable access to the internet. Regardless of typical work location, on occasion and at the discretion of the NCRI Director of Quality Assurance, the Senior Biostatistician may be required to be onsite at MGH for meetings, sponsor audits, or regulatory inspections. Advanced notice will be given. Periodic in-person attendance will be required at the discretion of supervisor.
Summary
Job Summary
Responsible for collecting data from medical research and analyzing it to draw conclusions or make predictions. Also responsible for developing and executing research studies in collaboration with other statisticians and scientists, monitoring clinical trials to ensure the integrity of the results.
Does this position require Patient Care?
No
Essential Functions
- Develop statistical analysis plans for clinical trials, observational studies, and other biomedical research projects.
- Conduct statistical analyses of data from all types of studies, including those with complex designs or requiring sophisticated statistical techniques; begin to oversee biostatisticians and/or statistical programmers.
- Generate reports of study progress, including reports for data and safety monitoring boards, and assist in the design of these reports.
- Develop programs and guide efforts to perform robust data manipulation and error detection to ensure data integrity.
- Provide statistical guidance for grants and other funding proposals.
- Assist in hiring, onboarding, training, and mentoring statistical programmers and biostatisticians.
Education
Master's Degree Statistics required or Master's Degree Related Field of Study required
Can this role accept experience in lieu of a degree?
No
Licenses and Credentials
Experience
Advanced Statistics/Biostatistics Experience 3-5 years required
Knowledge, Skills And Abilities
- Strong background in statistical programming using SAS or R.
- Strong communication skills, including proficiency in written and spoken English.
- Excellent attention to detail.
- Experience in supporting studies in all phases, from design through publication.
- Ability to explain statistical concepts to non-statistical collaborators.
Additional Job Details (if applicable)
- Standing Occasionally (3-33%)
- Walking Occasionally (3-33%)
- Sitting Constantly (67-100%)
- Lifting Occasionally (3-33%) 20lbs - 35lbs
- Carrying Occasionally (3-33%) 20lbs - 35lbs
- Pushing Rarely (Less than 2%)
- Pulling Rarely (Less than 2%)
- Climbing Rarely (Less than 2%)
- Balancing Occasionally (3-33%)
- Stooping Occasionally (3-33%)
- Kneeling Rarely (Less than 2%)
- Crouching Rarely (Less than 2%)
- Crawling Rarely (Less than 2%)
- Reaching Occasionally (3-33%)
- Gross Manipulation (Handling) Constantly (67-100%)
- Fine Manipulation (Fingering) Frequently (34-66%)
- Feeling Constantly (67-100%)
- Foot Use Rarely (Less than 2%)
- Vision - Far Constantly (67-100%)
- Vision - Near Constantly (67-100%)
- Talking Constantly (67-100%)
- Hearing Constantly (67-100%)
Hybrid
Work Location
399 Revolution Drive
Scheduled Weekly Hours
40
Employee Type
Regular
Work Shift
Day (United States of America)
Pay Range
$93,953.60 - $136,739.20/Annual
Grade
7
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement
1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Salary : $93,954 - $136,739