What are the responsibilities and job description for the Postdoctoral Fellow Krantz Family Center for Cancer Research position at Mass General Brigham?
Site: The General Hospital Corporation
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
A postdoctoral fellowship position is available in the lab of Dr. Steve Blum at the Massachusetts General Hospital Krantz Family Center for Cancer Research and Harvard Medical School. The Blum Lab develops safer and more effective cancer immunotherapies by integrating primary human samples, systems immunology, and disease-relevant models to uncover mechanisms of treatment toxicity and resistance. The lab’s long-term goal is to inspire new therapeutic strategies and improve clinical care by maximizing anti-tumor immunity while minimizing harm. Current efforts focus on two major challenges:
The Blum Lab values teamwork, scientific rigor, and curiosity, and it is committed to providing a supportive training environment. The lab is located in a state-of-the-art research building on the main MGH campus in Boston, MA, surrounded by world-class investigators across multiple disciplines. The lab is affiliated with the MGH Department of Medicine, the MGH Cancer Center, Harvard Medical School, and the Broad Institute of MIT & Harvard, providing access to cutting-edge technologies and opportunities for collaboration across Boston’s vibrant biomedical community.
Key Responsibilities
Interested applicants should email a cover letter, CV, and contact information for three references to Dr. Steve Blum (sblum@mgh.harvard.edu). Please include in the email subject “Postdoc Application: Blum Lab”.
Please do not apply through this link.
Additional Job Details (if Applicable)
Remote Type
Onsite
Work Location
55 Fruit Street
EEO Statement
1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
A postdoctoral fellowship position is available in the lab of Dr. Steve Blum at the Massachusetts General Hospital Krantz Family Center for Cancer Research and Harvard Medical School. The Blum Lab develops safer and more effective cancer immunotherapies by integrating primary human samples, systems immunology, and disease-relevant models to uncover mechanisms of treatment toxicity and resistance. The lab’s long-term goal is to inspire new therapeutic strategies and improve clinical care by maximizing anti-tumor immunity while minimizing harm. Current efforts focus on two major challenges:
- Peritoneal metastases and malignant ascites - The lab seeks to better understand the biology of this immunosuppressive microenvironment and identify novel therapeutic opportunities.
- Immune-related adverse events (irAEs) - The lab seeks to understand the drivers of the potentially dangerous complications caused by immune checkpoint inhibitors and their relationship to anti-tumor responses to identify better models, therapeutic strategies, and biomarkers.
The Blum Lab values teamwork, scientific rigor, and curiosity, and it is committed to providing a supportive training environment. The lab is located in a state-of-the-art research building on the main MGH campus in Boston, MA, surrounded by world-class investigators across multiple disciplines. The lab is affiliated with the MGH Department of Medicine, the MGH Cancer Center, Harvard Medical School, and the Broad Institute of MIT & Harvard, providing access to cutting-edge technologies and opportunities for collaboration across Boston’s vibrant biomedical community.
Key Responsibilities
- Lead and execute wet-lab experiments using patient-derived samples and relevant model systems
- Analyze and interpret results in conjunction with computational and clinical collaborators
- Prepare figures, present findings, drive manuscripts, and craft fellowship/grant applications
- Contribute to a rigorous, collaborative lab culture through teamwork and discussion
- Mentor junior trainees as appropriate
- Highly motivated and organized individual excited to work in a collaborative, fast-paced environment
- PhD, MD/PhD, or MD with research training in biological sciences
- Proficiency in basic molecular biology, tissue culture, and biochemical techniques
- Experience with flow cytometry, fluorescence microscopy, organoid models, immune cell engineering, multi-omics workflows, and/or quantitative analysis is preferred but not required.
- Excellent communication, organization, and teamwork skills
- First-authored publication(s) of scientific work
Interested applicants should email a cover letter, CV, and contact information for three references to Dr. Steve Blum (sblum@mgh.harvard.edu). Please include in the email subject “Postdoc Application: Blum Lab”.
Please do not apply through this link.
Additional Job Details (if Applicable)
Remote Type
Onsite
Work Location
55 Fruit Street
EEO Statement
1200 The General Hospital Corporation is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.