What are the responsibilities and job description for the Amplify Chemist position at Mass General Brigham?
Site: Mass General Brigham Incorporated
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The Amplify Chemist will act as an internal expert to aid in the evaluation of technologies as well as the operation of funded medicinal chemistry projects within the Amplify portfolio. The Amplify Chemist will provide technical expertise in evaluating molecules for candidate projects as part of the investment triage and diligence process culminating in plan development and approval.
This role will report to the Chemistry Project Lead and work closely with other Leads, Operating Partners, and Amplify Leadership on multiple programs. The Amplify Chemist may also participate in commercialization activities including pitching to external investors and partners.
Operationally, the Amplify Chemist will leverage their expertise in medicinal chemistry from early drug discovery through to clinical-scale synthesis for funded programs, and engage with academic investigators and vendors to generate and analyze new molecules.
The ideal candidate will have participated in fundraising and early stage company science and drug discovery operations.
The Amplify Chemist will be a vital contributor to the success of Amplify in translating promising new idea to reality, and creating value with these new technologies.
Onsite travel as needed
Qualifications
Education
Remote Type
Remote
Work Location
399 Revolution Drive
Scheduled Weekly Hours
20
Employee Type
Regular
Work Shift
Day (United States of America)
Pay Range
$144,206.40 - $209,757.60/Annual
Grade
9
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement
Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Mass General Brigham relies on a wide range of professionals, including doctors, nurses, business people, tech experts, researchers, and systems analysts to advance our mission. As a not-for-profit, we support patient care, research, teaching, and community service, striving to provide exceptional care. We believe that high-performing teams drive groundbreaking medical discoveries and invite all applicants to join us and experience what it means to be part of Mass General Brigham.
Job Summary
The Amplify Chemist will act as an internal expert to aid in the evaluation of technologies as well as the operation of funded medicinal chemistry projects within the Amplify portfolio. The Amplify Chemist will provide technical expertise in evaluating molecules for candidate projects as part of the investment triage and diligence process culminating in plan development and approval.
This role will report to the Chemistry Project Lead and work closely with other Leads, Operating Partners, and Amplify Leadership on multiple programs. The Amplify Chemist may also participate in commercialization activities including pitching to external investors and partners.
Operationally, the Amplify Chemist will leverage their expertise in medicinal chemistry from early drug discovery through to clinical-scale synthesis for funded programs, and engage with academic investigators and vendors to generate and analyze new molecules.
The ideal candidate will have participated in fundraising and early stage company science and drug discovery operations.
The Amplify Chemist will be a vital contributor to the success of Amplify in translating promising new idea to reality, and creating value with these new technologies.
Onsite travel as needed
Qualifications
Education
- Bachelor's Degree Chemistry required or Bachelor's Degree Related Field of Study required and Master's Degree Related Field of Study preferred
- Medicinal Chemistry in the biotech or pharmaceutical industry setting 8-10 years required and Experience in participation in early stage company science and drug discovery operations 5-7 years required
- Extensive working knowledge of modern medicinal chemistry design and drug discovery techniques (FBDD, SBDD, multi-attribute analysis, flexible resourcing models, alternative delivery systems, etc.).
- Solid knowledge of partner disciplines related to drug discovery (e.g., pharmacology, ADMET-DMPK, toxicology, etc.).
- Proven ability to effectively manage CRO-based drug development and medicinal chemistry activities in library/screening as well as molecule design frameworks.
- Has a track record of delivering multiple drugs from hit to IND.
- Experience across a range of indications (e.g., cardiovascular, immunology, neuroscience, oncology), target classes, and chemistries is essential.
- Independently develops and delivers required draft documents such as scope, proposals, timeline, critical path, and budget options for stakeholder review and team-level execution.
- Ability to manage multiple projects with competing priorities.
Remote Type
Remote
Work Location
399 Revolution Drive
Scheduled Weekly Hours
20
Employee Type
Regular
Work Shift
Day (United States of America)
Pay Range
$144,206.40 - $209,757.60/Annual
Grade
9
At Mass General Brigham, we believe in recognizing and rewarding the unique value each team member brings to our organization. Our approach to determining base pay is comprehensive, and any offer extended will take into account your skills, relevant experience if applicable, education, certifications and other essential factors. The base pay information provided offers an estimate based on the minimum job qualifications; however, it does not encompass all elements contributing to your total compensation package. In addition to competitive base pay, we offer comprehensive benefits, career advancement opportunities, differentials, premiums and bonuses as applicable and recognition programs designed to celebrate your contributions and support your professional growth. We invite you to apply, and our Talent Acquisition team will provide an overview of your potential compensation and benefits package.
EEO Statement
Mass General Brigham Incorporated is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. To ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Veteran’s Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact Human Resources at (857)-282-7642.
Mass General Brigham Competency Framework
At Mass General Brigham, our competency framework defines what effective leadership “looks like” by specifying which behaviors are most critical for successful performance at each job level. The framework is comprised of ten competencies (half People-Focused, half Performance-Focused) and are defined by observable and measurable skills and behaviors that contribute to workplace effectiveness and career success. These competencies are used to evaluate performance, make hiring decisions, identify development needs, mobilize employees across our system, and establish a strong talent pipeline.
Salary : $144,206 - $209,758