Demo

Engineering Manager

Mandolin
San Francisco, CA Full Time
POSTED ON 4/11/2026
AVAILABLE BEFORE 5/6/2026
About Mandolin

Nearly every disease will become treatable in our lifetimes. Mandolin is laying the clinical and financial infrastructure to get groundbreaking treatments to patients faster, powered by AI agents.

Mandolin partners closely with the largest healthcare institutions in the US, covering more than $10B drug spend across the country. We're backed by Greylock, SV Angel, Maverick, SignalFire, and the founders of Vercel, Decagon, and Yahoo.

Why we need you

As a Engineering Manager, you’ll be a critical multiplier on our technical team — leading high-performing engineers, shaping our engineering culture, and ensuring we ship robust, scalable systems. You’ll play a hands-on role in both people leadership and technical execution, helping the team navigate complex architecture, rapid iteration cycles, and customer-driven development in a fast-moving environment. You’ll be responsible for growing the team, ensuring technical excellence, and helping us deliver high-impact products that directly improve patient access to life-saving therapies.

What You’ll Do

  • Lead, mentor, and grow a team of engineers building core platform functionality and AI workflows
  • Partner closely with Product, Design, and Forward Deployed Engineering to prioritize work and drive execution
  • Maintain a high bar for technical design, system architecture, and engineering quality
  • Help scale our engineering culture and team through recruiting, onboarding, and performance development
  • Foster a fast-paced but sustainable environment where engineers are empowered to do their best work
  • Contribute to strategic planning and help shape Mandolin’s technical roadmap as we expand into new verticals

Must-have Experience

  • 5 years of engineering management experience in a fast-paced environment
  • Track record of leading teams that ship complex, production-grade systems
  • Strong technical background with the ability to go deep in backend systems, infrastructure, or AI/ML tooling
  • Proven ability to collaborate cross-functionally with product, design, and customer-facing teams
  • Excellent communication, prioritization, and organizational skills in ambiguous, fast-changing contexts

Nice-to-haves

  • Experience at an early-stage startup or in the healthcare/healthtech space
  • Exposure to LLMs, agent frameworks, and AI infrastructure
  • Familiarity with modern cloud platforms, data pipelines, and secure integrations in regulated environments
  • Strong opinions on team processes, and the humility to evolve them as the company scales

Salary.com Estimation for Engineering Manager in San Francisco, CA
$183,002 to $221,304
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Job openings at Mandolin

  • Mandolin San Francisco, CA
  • About Mandolin Nearly all disease will become treatable in our lifetimes, and drug discovery is quickly becoming an engineering discipline. Mandolin is bui... more
  • 13 Days Ago


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