Demo

Machine Learning Engineer

latent
San Francisco, CA Full Time
POSTED ON 9/27/2025
AVAILABLE BEFORE 10/27/2025

Latent is building the intelligence infrastructure for American healthcare. Our products are already helping hospitals and clinics dramatically increase workflow output, speed up patient access to medications, and boost provider revenue. Our flagship multi-modal search and question-answering platform analyzes EHR data to surface the most relevant information, reducing operational overhead and improving care delivery.

We’re a small, mission-driven team backed by General Catalyst, Conviction, and YC, tackling some of healthcare’s hardest technical challenges. If you're passionate about applying cutting-edge machine learning in a high-stakes domain, we’d love to meet you.

About the Role

As a Machine Learning Engineer at Latent, you’ll design and deploy advanced models at the frontier of medical language understanding. You will develop systems that can interpret long-form clinical text, generate auditable justifications for medical decisions, and reason over structured and unstructured data to automate the prior authorization process end-to-end. 

You’ll work on some of the most pressing problems in applied AI—balancing model expressiveness with verifiability, maintaining safety in open-ended generation, and scaling LLMs to production in high-stakes environments. This is a rare opportunity to bring research into production at the edge of what’s possible in medicine and AI.

This is a high-impact, high-ownership role based full-time onsite in our San Francisco office.

What You’ll Do

  • Train and fine-tune large open-source language models for clinical reasoning, medical question answering, and evidence-grounded generation, where the stakes are human health
  • Design and scale multimodal embeddings to encode clinical documents, structured EHRs, and payer policies in a unified space
  • Own the lifecycle of ML systems—from research prototypes to fault-tolerant, privacy-compliant services running in production
  • Build robust retrieval pipelines for real-time semantic search and RAG architectures in the clinical domain
  • Collaborate with clinicians, engineers, and product leaders to ensure outputs are interpretable, auditable, and aligned with real-world constraints
  • Contribute to a culture of ML excellence through code reviews, experimentation frameworks, and internal knowledge sharing

You Might Be a Fit If You…

  • Have a strong foundation in ML research or systems—through an advanced degree or high-impact work in industry
  • Have deep experience with NLP and LLMs (e.g., fine-tuning, LoRA, RAG, quantization) and are comfortable with frameworks like PyTorch, Hugging Face, and LangChain
  • Have shipped ML models in production environments—especially where latency, safety, or interpretability were critical
  • Are excited by ambiguous, zero-to-one problems and can think creatively about tradeoffs between performance, explainability, and reliability
  • Thrive in fast-moving, ambiguous, enjoy working on open-ended technical challenges, and work well with minimal oversight
  • (Bonus) Have published ML research or contributed to the broader ML community
  • (Bonus) Have worked with clinical, biomedical, or claims data—or are excited to learn the domain deeply

Compensation

The expected salary range for this role is $140,000 to $240,000 annually, in addition to equity and comprehensive benefits. Compensation packages are highly variable based on a variety of factors including experience and expertise. If your compensation expectations fall outside this range, we still encourage you to apply.

Why You Should Join Us

  • Backed by top investors: General Catalyst, Conviction, and YC
  • Tight-knit, world-class team with a deep sense of mission
  • Huge greenfield opportunity with significant ownership and room for growth
  • Competitive salary and equity compensation. The equity upside of an early-stage startup with the product-market fit of a later-stage company.
  • Excellent benefits and versatile health, dental, and vision coverage plans
  • Paid parental leave
  • Lunch and dinner provided at the office
  • Unlimited PTO

Salary : $140,000 - $240,000

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Machine Learning Engineer?

Sign up to receive alerts about other jobs on the Machine Learning Engineer career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$123,167 - $152,295
Income Estimation: 
$146,673 - $180,130
Income Estimation: 
$149,493 - $192,976
Income Estimation: 
$184,796 - $233,226
Income Estimation: 
$77,900 - $95,589
Income Estimation: 
$101,387 - $124,118
Income Estimation: 
$101,387 - $124,118
Income Estimation: 
$119,030 - $151,900
Income Estimation: 
$119,030 - $151,900
Income Estimation: 
$149,493 - $192,976
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Job openings at latent

latent
Hired Organization Address San Francisco, CA Full Time
Latent is solving complex challenges in healthcare through robust and reliable Medical Intelligence. Our AI-driven solut...
latent
Hired Organization Address San Francisco, CA Full Time
Latent is building the intelligence infrastructure for American healthcare. Our products are already helping hospitals a...

Not the job you're looking for? Here are some other Machine Learning Engineer jobs in the San Francisco, CA area that may be a better fit.

Machine Learning Research Scientist / Machine Learning Engineer

Calico Life Sciences, South San Francisco, CA

Machine Learning Engineer Intern

Cognitiv, San Mateo, CA

AI Assistant is available now!

Feel free to start your new journey!