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Postdoctoral Fellow (Li/Saphire Lab)

La Jolla Institute for Allergy and Immunology
La Jolla, CA Full Time
POSTED ON 5/15/2026
AVAILABLE BEFORE 7/15/2026

Postdoctoral Researchers in Structural Immunology and Immunotherapy Development

A rising research team at the La Jolla Institute for Immunology (LJI) is seeking highly creative and motivated postdoctoral researchers to join our mission of discovering novel immunoregulatory mechanisms and architecting next-generation immunotherapeutics. This independent team and establishing laboratory, led by Dr. Haoyang Li, is supported by multi-year NIH R01 and R21 research funds, and the research direction focuses on bridging structural biology with protein/antibody engineering to modulate immune signaling in curing autoimmune diseases, infectious diseases and cancers.

Qualification and Requirement:

Candidates should have a doctoral degree in structural biology or immunology with preferred experience in:

Structural Biology: protein design and engineering, cryoEM sample preparation, data collection and structural analysis.

Immunology: immune signaling discovery, antibody discovery, and autoimmunity/cancer disease models (animal models or organoids)

Motivation and Innovation: a strong desire to advance both basic immunological discoveries and translational therapeutic design.

Why Join the Li Lab at LJI?

Cutting-Edge Infrastructure: Unfettered access to state-of-the-art facilities, including CryoEM Core, Animal Study Core, Clinical Studies Core, Bioinformatics Core, Antibody Discovery Center, NGS core, Microscopy & Histology Core and Flow Cytometry Core.

Collaborative Environment: Study at a world-class immunology institute in the heart of the San Diego biomedical hub with close collaborations to other Tier 1 institutions and biotechs, benefiting from a unique "mechanism-to-therapeutic" pipeline.

Mentorship: Join a vibrant, newly funded team where you will receive direct mentorship from the PI and support from established immunologists within the network to navigate the transition to independent scientific leadership.

How to Apply?

Candidates should include their curriculum vitae, a cover letter including a brief statement of research interests, and the contact information of three references. Please enclose all documents within a single file attachment.

The La Jolla Institute for Immunology (LJI) offers a collegial work environment that emphasizes collaboration, teamwork and creativity. Full-time employment at LJI includes a competitive salary, medical/dental/vision benefits, paid sick leave, and contributions to a retirement plan (403B). For the last decade, LJI has been ranked as one of the best places to work in San Diego by the San Diego Business Journal. The Institute hosts world-renowned faculty and over 80 postdoctoral researchers with scientists from over 30 countries. LJI is located in the Science Research Park on the campus of UC San Diego, providing easy access to the San Diego life sciences community and all that the area has to offer.

LJI provides Equal Employment Opportunity (EEO) to all employees and applicants for employment, and prohibits discrimination and harassment of any type, regardless of race, color, religion, age, sex, national origin, marital status, disability status, genetics, medical conditions, protected veteran status, sexual orientation, gender identity or expression, reproductive health decisions, or pregnancy, or any other condition protected by state and local laws. This applies to all terms and conditions of employment, including recruitment, hiring, placing, training, promotion, compensation, benefits, transfers, educational assistance, terminations, layoffs, recalls, transfers, leaves of absences, and social and recreational programs.

La Jolla Institute is committed to compensation that is externally competitive and internally equitable. We validate this commitment by conducting regular market analyses to remain competitive with organizations of similar size in the nonprofit, independent research sector. Compensation decisions consider a variety of factors including experience, education, unique skill sets, organizational need, and internal equity.

 

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$144,244 to $181,472
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