What are the responsibilities and job description for the Senior Research Associate position at Kymera Therapeutics?
Who we are:
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.
How we work:
Kymera is a clinical-stage biotechnology company pioneering the field of targeted protein degradation (TPD) to develop medicines that address critical health problems and have the potential to dramatically improve patients’ lives. Kymera is deploying TPD to address disease targets and pathways inaccessible with conventional therapeutics. Having advanced the first degrader into the clinic for immunological diseases, Kymera is focused on building an industry-leading pipeline of oral small molecule degraders to provide a new generation of convenient, highly effective therapies for patients with these conditions. Founded in 2016, Kymera has been recognized as one of Boston’s top workplaces for the past several years. For more information about our science, pipeline and people, please visit www.kymeratx.com or follow us on X (formerly Twitter) or LinkedIn.
How we work:
- PIONEER: We are courageous, resilient and rigorous in our mission to improve patients’ lives through our revolutionary degrader medicines.
- COLLABORATE: We value trust transparency from everyone. Our goals are shared, our decisions data-driven and our camaraderie genuine.
- BELONG: We recognize our differences, inviting curiosity and inclusivity, so that our people are valued, seen, and heard.
- Develop quantitative cell-based assays to facilitate SAR and MOA studies for novel degraders.
- Perform various solution and plate based assays to evaluate changes in biomarkers from primary human cells and animal models.
- Maintain good written records of laboratory procedures and communicate research findings in cross-functional project team meetings.
- Review literature and conference proceedings to identify emerging technologies/assays and execute exploratory efforts for internal validation.
- BS with 5 years or MS with 2 years of relevant lab experience in immunology
- Mammalian cell culture experience including both immortalized and primary human cells
- Proficiency with molecular and cell biology techniques including ELISA, MSD, AlphaLISA, western blot, and flow cytometry
- Independent mindset to execute experiments, analyze, and interpret results with minimal supervision while proactively seeking help and guidance.
- Excellent organizational, verbal, and written communication skills and familiarity with electronic laboratory notebooks (ELN).
- Previous experience in TPD is desirable but not required; innovative and growth mindset to execute and learn new things is essential.