Director, Sales Operations

Kiniksa Pharmaceuticals is a commercial‑stage biopharmaceutical company developing and commercializing novel therapies for diseases with unmet need, with a focus on cardiovascular indications. With deep expertise in immunology and inflammation, Kiniksa is advancing a growing portfolio of approved and investigational medicines, anchored by its lead product, ARCALYST®, the first and only FDA‑approved therapy for recurrent pericarditis. Grounded in rigorous science and bold innovation, the company fosters a highly collaborative, patient‑first culture led by accomplished life sciences leaders. At Kiniksa, talented individuals are trusted and empowered to make a real impact—shaping the future of medicine while improving the lives of patients who need it most.

We are seeking a dynamic, analytically driven, and execution-focused Director, Sales Operations to lead and scale the operational pillars of our sales organization. This role is critical in supporting our rapid growth and ensuring our field teams are equipped, informed, and empowered to deliver exceptional performance.

This role will report to the Group Vice President, Commercial Operations and act as a senior member of the Commercial Operations team, partnering closely with Sales Leadership, Marketing, Market Access, Compliance, Patient Services, Finance, and IT to drive strategic decision-making and ensure flawless execution across the commercial ecosystem.

You will oversee the processes, insights, and operational rigor that enable the successful commercialization of ARCALYST and future therapies. This position is based in our Lexington, MA office and follows a hybrid schedule of four days in the office and one day remote.

Responsibilities (including But Not Limited To)

• Incentive Compensation:
• Lead the strategy, design, modeling, and administration of the field IC program.
• Partner with Sales Leadership to ensure IC plans are competitive, equitable, motivating, and aligned to brand and corporate goals.
• Deliver timely and accurate IC reporting, payout calculations, and field communications to maintain trust and transparency.
• Structure, Sizing, and Alignments:
• Own the development, maintenance, and optimization of sales force structure, territory alignments, and targeting strategies.
• Leverage analytics, segmentation, and forecasting to inform sizing decisions and ensure optimal coverage and productivity.
• Fleet Management:
• Oversee fleet strategy, vendor management, policy development, training, and operational execution for all field vehicles.
• Evaluate opportunities for cost efficiency, improved user experience, and enhanced scalability.
• Field Operations
• Serve as a trusted advisor to the VP of Sales, providing data-driven recommendations that influence strategy and execution.
• Partner with other members of the Commercial Operations team to ensure seamless onboarding, training, and support for field teams across all systems, reports, and tools.
• Deliver high-quality operational processes and reports that support roster management, field credentialling, and access to data and insights.
  

Standout Skills For Impact

• You excel at:
• Translating complex datasets and operational processes into clear, actionable recommendations.
• Balancing strategic vision with hands-on execution in a fast‑paced, high‑growth environment.
• Anticipating operational needs and proactively designing scalable solutions.
• Communicating with clarity, confidence, and influence across levels.
• Driving alignment and partnership across diverse teams.
• Maintaining a relentless focus on compliance, quality, and continuous improvement.
  
  

Qualifications And Experience

• Requires a BA or BS (MS or MBA preferred) with 8 years of relevant sales effectiveness / sales force automation experience; Pharmaceutical/Biotech or Lifesciences experience required
• Launch experience preferred
• Experience with implementing field CRM systems (e.g. Salesforce, Veeva, IQVIA OCE)
• Excellent oral, written, and presentation skills--able to explain complex concepts clearly to a variety of audiences
• Must thrive working in a fast-paced, innovative environment while remaining flexible, proactive, resourceful and efficient
• Excellent interpersonal skills, ability to develop important relationships with key stakeholders, good conflict management and negotiation skills, ability to analyze complex issues to develop relevant and realistic plans and recommendations
• Strong commitment to compliance and ethical standards
• Requires travel ~10% of time
  
  

Compensation decisions are based on objective criteria including role responsibilities, experience/qualifications, internal equity, geographic location, and external market benchmarks.

Pay Range

$210,000 - $230,000 USD

Kiniksa is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, transgender status, age, genetics, national origin, protected veteran status, or disability status, or any other legally protected category. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Kiniksa does not accept unsolicited resumes from staffing agencies or search firms. Any resumes submitted without a signed agreement will be considered property of Kiniksa, and no fees will be paid.