Demo

Senior Scientist - Principle Scientist Mass Spec Core

KBI Biopharma
Boulder, CO Full Time
POSTED ON 10/8/2026
AVAILABLE BEFORE 11/13/2026
At KBI Biopharma, we are advancing science and accelerating breakthroughs. As a global leader in biopharmaceutical development and manufacturing, we empower life science companies to bring new medicines and vaccines to the world faster. Explore your potential at KBI, where innovation meets impact.

Position Summary:

KBI Biopharma is seeking a highly skilled and motivated Senior Level Analytical Scientist to join our Analytical and Formulation Sciences (AFS) team in Boulder, CO. This role is ideal for a PhD-level scientist with deep expertise in protein analytics by LC-MS. You will serve as a subject matter expert (SME), driving innovation and excellence in analytical testing by mass spectrometry to support integrated client programs from early development through commercialization. This position collaborates cross-functionally with process development, characterization, and regulatory teams.

Responsibilities:

  • Design and strategically execute analytical experiments in support of biotherapeutics Process Development.
  • Demonstrate expertise in LC-MS, HPLC/UPLC, and other common analytical techniques.
  • Design and implement analytical strategies to support product development and regulatory submissions.
  • Generate high-quality documentation suitable for publication and regulatory review. Act as SME on client programs, providing technical guidance and representing KBI in client interactions.
  • Mentor and train junior scientists and associates.
  • Perform peer reviews of data and reports related to method development, qualification, and validation.
  • Manage timelines and resources to meet project milestones.
  • Advise leadership on program status and technical challenges.
  • Contribute to continuous improvement initiatives within the AFS team.


Requirements:

  • Ph.D. in Biophysics, Biochemistry, Analytical Chemistry, Biochemical Engineering and 4 years of experience for Senior
  • Ph.D and 6 years of experience for Principal
  • Able to react to change and handle other essential tasks as assigned. Adhere to all safety requirements and assure that departmental employees comply with required safety procedures.
  • Strong understanding of protein structure, aggregation, and higher-order structure analysis.
  • Excellent communication skills and ability to present complex data to diverse audiences.
  • Proficiency in scientific software and data analysis tools.
  • Ability to work independently and collaboratively in a fast-paced environment.
  • Working knowledge of the Process Development functional area with aptitude in fermentation development for protein expression and downstream (purification) operations (chromatography, TFF, refold, conjugation) a plus


Salary:

Senior Scientist: $118,000-$148,000

Principal Scientist: $133,000-$167,000

KBI Biopharma, Inc. is an EEO/AA employer and actively seeks to diversify its work force. Therefore, all qualified applicants, regardless of race, color, national origin, religion, gender, gender identity, sexual orientation, age, disability or veteran status, are strongly encouraged to apply.

I understand that neither the completion of this application nor any other part of my consideration for employment establishes any obligation for KBI Biopharma, Inc. to hire me. If I am hired, I understand that either KBI Biopharma, Inc. or I can terminate my employment at any time and for any reason, with or without cause and without prior notice. I understand that no representative of KBI Biopharma, Inc. has the authority to make any assurance to the contrary.

I attest with my signature below that I have given to KBI Biopharma, Inc. true and complete information on this application. No requested information has been concealed. I authorize KBI Biopharma, Inc. to contact references provided for employment reference checks. If any information I have provided is untrue, or if I have concealed material information, I understand that this will constitute cause for the denial of employment or immediate dismissal.

Salary : $118,000 - $148,000

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