Demo

Senior Manager-Clinical Bioinformatics Operations

Jobs via Dice
Marlborough, MA Full Time
POSTED ON 6/1/2026
AVAILABLE BEFORE 6/30/2026
RESPONSIBILITIES:

Kforce has a client that is seeking a Senior Manager, Clinical Bioinformatics Operations in Marlborough, MA.

The Opportunity:

A leading national health technology firm is seeking a high-caliber Senior Manager of Bioinformatics Operations to lead a regional team dedicated to scaling high-throughput clinical diagnostics. In this leadership role, you will bridge the gap between complex genomic engineering and daily lab operations, ensuring our precision medicine pipeline remains stable, compliant, and cutting-edge.

The Role:

As a regional operational lead, you will oversee the deployment, validation, and maintenance of automated computational pipelines. You will partner with cross-functional stakeholders-including laboratory scientists, IT infrastructure, and R&D engineers-to deliver high-quality diagnostic applications that meet rigorous clinical turnaround times and regulatory standards.

Key Responsibilities:

  • Team Leadership: Mentor a regional team of 5-7 bioinformatics scientists and contractors, fostering a culture of technical excellence and accountability
  • Operational Oversight: Manage daily production pipelines, ensuring 24/7 service levels and performance targets are met for patient reporting
  • Production Support: Collaborate with wet-lab operations to troubleshoot processing issues and manage incident response for production environments
  • Process Engineering: Drive best practices in CI/CD, workflow orchestration, and system health monitoring to ensure "always-on" availability
  • Compliance & Data Integrity: Maintain robust documentation for regulatory audits and ensure secure, compliant archival of sensitive genomic data
  • Strategic Alignment: Partner with peer managers to standardize operational frameworks and support the rollout of new diagnostic products
  • Professional Development: Implement training modules and competency assessments to upskill the technical team

REQUIREMENTS:

  • Experience: 7 years in bioinformatics, computational biology, or software engineering within a production environment
  • Technical Stack: Proficiency in Python, R, Shell scripting, SQL, and cloud architecture (AWS preferred)
  • Domain Expertise: Hands-on experience with secondary analysis tools (aligners, variant callers) and clinical interpretation workflows
  • Leadership: Proven track record of managing technical teams and delivering "clinical-grade" software solutions
  • Regulatory Knowledge: Familiarity with high-complexity laboratory environments (e.g., CAP/CLIA or similar quality frameworks)
  • Communication: Ability to translate complex technical challenges into actionable strategy for non-technical stakeholders

Preferred Experience:

  • Advanced degree (MSc or PhD) in a relevant computational field
  • Experience integrating with LIMS or third-party variant interpretation platforms
  • Familiarity with Agile methodologies and managing distributed or international teams

Why Join Us:

We offer a mission-driven environment focused on transforming patient care through data. Our benefits package includes comprehensive health insurance, retirement matching, tuition reimbursement, and clear pathways for executive leadership growth.

The pay range is the lowest to highest compensation we reasonably in good faith believe we would pay at posting for this role. We may ultimately pay more or less than this range. Employee pay is based on factors like relevant education, qualifications, certifications, experience, skills, seniority, location, performance, union contract and business needs. This range may be modified in the future.

We offer comprehensive benefits including medical/dental/vision insurance, HSA, FSA, 401(k), and life, disability & ADD insurance to eligible employees. Salaried personnel receive paid time off. Hourly employees are not eligible for paid time off unless required by law. Hourly employees on a Service Contract Act project are eligible for paid sick leave.

Note: Pay is not considered compensation until it is earned, vested and determinable. The amount and availability of any compensation remains in Kforce's sole discretion unless and until paid and may be modified in its discretion consistent with the law.

This job is not eligible for bonuses, incentives or commissions.

Kforce is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, pregnancy, sexual orientation, gender identity, national origin, age, protected veteran status, or disability status.

By clicking ?Apply Today? you agree to receive calls, AI-generated calls, text messages or emails from Kforce and its affiliates, and service providers. Note that if you choose to communicate with Kforce via text messaging the frequency may vary, and message and data rates may apply. Carriers are not liable for delayed or undelivered messages. You will always have the right to cease communicating via text by using key words such as STOP.

Salary.com Estimation for Senior Manager-Clinical Bioinformatics Operations in Marlborough, MA
$94,494 to $118,293
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