Scientist II - Bioconjugation and Delivery

Software Guidance & Assistance, Inc., (SGA), is searching for a Scientist II - Bioconjugation and Delivery for a contract assignment with one of our premier Pharmaceutical clients in South San Francisco, CA.

Responsibilities :

• Responsible for the design and generation of new therapeutic modalities that combine the engineering and analytical principles of multiple scientific disciplines. We are excited to be at the forefront of therapeutic design by generating molecules with unique mechanisms of action. We are seeking a talented early-in-career Scientist to join our team to advance our mission by learning and applying advanced bioconjugation techniques with precise analytical characterization. This position offers hands-on experience in drug development, including protein bioconjugation.
• Bioconjugation of proteins utilizing chemical and/or enzymatic conjugation methods, including reaction design and optimization.
• Development, optimization, and implementation of purification protocols of bioconjugates using common protein purification techniques.
• Analytical characterization of reaction mixtures and purified conjugates employing chromatographic techniques (e.g. SEC, HIC, IEX), SDS-PAGE, colorimetric assays, as well as 1D and 2D mass spectrometry.
• Data reporting, interpretation of results, and data presentation to internal teams.
• Sample management of completed conjugates and related starting materials using internal inventory systems.
• Collaboration with scientists from multiple functional and therapeutic areas at the firm to advance molecules through the drug discovery pipeline.
  
  

Required Skills:

• Bachelor's Degree or higher in Chemistry, biochemistry, chemical biology, biophysics, biology, biomedical engineering, or related fields.
• Basic understanding of protein purification and analytical techniques.
• Previous experience with FPLC, HPLC or LCMS.
• Excellent communication, collaboration, and interpersonal skills.
  
  

Preferred Skills:

• Previous experience with oligonucleotides and/or antibody oligonucleotide generation
  
  

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at .

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities. Please visit our company to request an accommodation or assistance regarding our policy