Demo

Principal / Senior Scientist, Immunology

Janux Therapeutics
San Diego, CA Full Time
POSTED ON 3/29/2026
AVAILABLE BEFORE 5/28/2026

Janux Therapeutics is seeking a highly motivated Principal Scientist with demonstrated skills in the field of cancer immunology and/or immune cell biology. The incumbent will develop and troubleshoot cell-based assays for pre-clinical programs. These studies will aid in better understanding of MoA and in differentiation from competition. This person will mentor or manage more junior members in the immunology team, as well as interact closely with members across functional teams. A successful candidate will have extensive hands-on experience with assay development and troubleshooting, lead the immunology team in laboratory research to ensure timelines are met, inspire and develop team members, and be accountable for meeting deliverables for the Immunology team. This position is approximately 30-50% hands-on bench work and requires the effective communication and documentation. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.

 

This position is approximately 30-50% hands-on bench work and requires the effective communication and documentation. The ideal applicant will be collaborative and team-oriented, self-motivated, possess excellent communication and organizational skills, and carry a strong commitment to excellence.

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EDUCATION, EXPERIENCE, KNOWLEDGE, SKILLS AND ABILITIES
• A PhD in a scientific discipline is common with a minimum of 4 years related experience; or postdoc-experience with 2 years relevant industry experience; BS with minimum 12 years; MS with minimum 10 years experience.
• Hands-on experience with development of multi-parameter flow cytometry (10 colors) assays.
• Proficiency in culture of primary human immune cells (ie. PBMCs) is required.
• Proficiency in flow analysis is required (ie. FlowJo, DIVA, FCS Express, CellEngine, or Cytobank).
• Proficiency in excel, PowerPoint and GraphPad Prism is required.
• Excellent oral and written communication skills.
• Ability to influence others with or without direct authority. 
• Experience working with external vendors is a plus.
• Effective troubleshooting and problem-solving skills.
• Success in this role requires great attention to detail with the ability to multitask.
• Skills to be an effective team player, strong individual contributor, self-motivated, flexible, and able to handle multiple tasks and deliver high-quality results under tight timelines.
• Strong organizational skills and related diligence with documentation is required.


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$145,000 - $174,000 a year
In addition to a competitive base salary ranging from $145,000 to $174,000, we offer stock options, restricted stock units, a stock purchase plan (ESPP) and a target bonus. Janux also provides a comprehensive benefits package for our employees and their families, which includes medical, dental, vision, and supplemental disability insurance.
Please note that the base salary range is a guideline, and individual total compensation will vary based on factors such as qualifications, skill level, competencies, internal equity and work location.
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Job Type: Full-time

 

Benefits:

·         Annual bonus program

·         Incentive stock option plan

·         401k plan with flat non-elective employer contribution

·         Comprehensive medical insurance with 90-100% employer-paid premiums

·         Dental and vision insurance

·         HSA, FSA, and supplemental insurance plans (life, disability, accident, critical illness, hospital indemnity)

·         Unlimited PTO

·         Generous holiday schedule; includes summer and winter company shutdown

·         Relocation assistance

 

Schedule:

·         Monday to Friday

 

Work authorization:

·         United States (Required)

 

Additional Compensation:

·         Annual targeted bonus %

 

Work Location:

·         On site (San Diego, CA)

 

EQUAL OPPORTUNITY EMPLOYER:

Janux Therapeutics, Inc. is an equal opportunity employer that is committed to providing a work environment free of harassment and discrimination based upon a protected category, as well as an environment free from retaliation for protected activity.



Notice to Recruiters and Third-Party Agencies

The Talent Acquisition team manages the recruitment and employment process for Janux. To protect the interests of all parties involved, Janux will only accept resumes from a recruiter once a fully-executed search agreement is in place. Agencies are hereby specifically directed not to contact Janux employees directly in an attempt to present candidates. Janux will consider any candidate for whom an Agency and/or Recruiter has submitted an unsolicited resume to have been referred, free of any charges or fees.

Salary : $145,000 - $174,000

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