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Executive Director, Program Team Lead

Jade Biosciences
Chicago, IL Full Time
POSTED ON 3/31/2026
AVAILABLE BEFORE 5/5/2026
About Jade Biosciences

Jade Biosciences is a clinical-stage biotechnology company focused on developing best-in-class therapies that address critical unmet needs in autoimmune diseases. Jade’s lead candidate, JADE101, targets the cytokine APRIL, and is currently being evaluated in a Phase 1 clinical trial for the treatment of immunoglobulin A nephropathy. Jade’s pipeline also includes JADE201, an afucosylated anti-BAFF-R monoclonal antibody, as well as JADE301, an undisclosed antibody candidate, both currently in preclinical development. Jade was launched based on assets licensed from Paragon Therapeutics, an antibody discovery engine founded by Fairmount. For more information, visit JadeBiosciences.com and follow the Company on LinkedIn.  

Role Overview

The Executive Director, Program Team Lead, will drive strategic management of one or more drug development programs. This individual will play an integral role in building and leading efficient and collaborative cross-functional teams to achieve program goals. This role requires broad expertise in drug development, strong communication and leadership abilities as well as skillful internal and external stakeholder engagement/management. This is a critical and highly visible role, making a substantial contribution to the company.

This position is fully remote and will report to the VP and Head of Portfolio Strategy and Management (PSM). Periodic travel to team and company events is required.

Key Responsibilities

  • Leads a Program Team of cross-functional experts to develop and execute an integrated program strategy to maximize the opportunity of the asset
  • Builds organizational alignment on program priorities and strategic objectives, ensuring milestones are clearly defined and understood
  • Synthesizes complex scientific, operational, and business information into clear, big‑picture insights that inform strategic decision‑making and drive results
  • Critically challenges program plan assumptions, timelines and budget and creates alternative scenarios to enable strategic and operational agility
  • Continuously incorporates evolving external clinical, regulatory, and commercial insights into the program strategy and adjusts plans as needed
  • Proactively identifies risks and drives team to develop mitigations
  • Drive program strategic decision-making; ensures the program is adequately resourced and provides active input/oversight of major budget-impacting decisions
  • Drives the team to out-of-box thinking and creative issue resolution
  • Acts as spokesperson for the program and represents program internally and externally

Qualifications

  • Outstanding proven team leadership skills and experience in a complex matrix environment
  • Masters degree with 15 years of experience or Doctoral degree with 10 years of experience with a scientific and/or business-leadership focus
  • 15 years in the life-sciences, biotech and pharmaceutical industry; rare disease and small company experience strongly preferred
  • At least 10 years equivalent multi-/ cross-functional leadership experience
  • Experience with development program leadership required; strong preference for candidates who have led teams through registrational trials and market authorization
  • Excellent relationship building skills and ability to influence to achieve desired outcome
  • Effective interpersonal and communication skills to bridge between scientific and business stakeholders
  • Broad and deep understanding of the drug development process and the operational requirements needed to execute it
  • Ability to objectively interpret and evaluate scientific data and competitive business information
  • Advanced level of basic science; biologics expertise desired
  • Foundational financial knowledge, including resource planning and management for headcount and budget

Position Location

This is a remote role; periodic travel to team and company events is required.

The anticipated salary range for candidates for this role is $270,000 - $290,000. The final salary offered will depend on several factors, which may include, but not limited to, relevant years of experience, educational background, and geography.

As part of the I-9 verification of authorization to work in the United States, Jade Bioscience participates in E-Verify. To learn more about E-Verify please review this poster.

Jade Biosciences is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

Salary : $270,000 - $290,000

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