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Director, Global Market Access

Ionis Pharmaceuticals
Boston, MA Full Time
POSTED ON 9/23/2026
AVAILABLE BEFORE 10/22/2026

Headquartered in Carlsbad, California, and with offices in Boston, Massachusetts, and Dublin, Ireland, Ionis has been at work for more than three decades discovering medical breakthroughs that have redefined life for people with serious diseases. We’re pioneers in RNA-targeted medicines, and our platform continues to revolutionize drug discovery and transform lives for patients with unmet needs.  With multiple marketed medicines and a leading pipeline in neurology, cardiology and select areas of high patient needs, we continue to drive innovation in RNA therapies in addition to advancing new approaches in gene editing to provide greater value to patients and are well positioned financially to deliver on our strategic goals.

At Ionis, we pride ourselves on cultivating a challenging, motivating and rewarding environment that fosters innovation and scientific excellence. We know that our success is a direct result of the exceptional talents and dedication of our employees. 

With an unprecedented opportunity to change the course of human health, we look to add diverse individuals, skill sets and perspectives to our exceptional team. We continue to invest time, money and energy into making our onsite, hybrid and remote work environments a place where solid and lasting relationships are built and where our culture and employees can thrive. 

We’re building on our rich history, and we believe our greatest achievements are ahead of us. If you’re passionate about the opportunity to have meaningful impact on patients in need, we invite you to apply and join us. Experience and contribute to our unique culture while you develop and expand your career!

 

DIRECTOR, GLOBAL MARKET ACCESS

 

SUMMARY: 

Ionis is seeking a strategic and collaborative Director, Global Market Access to help shape development programs through strategic pricing and market access requirements across select assets in our pipeline for US and other key global markets. This individual will also closely partner with the US market access team, Ionis’ ex-US commercialization partner sand cross-functional leaders across Ionis. 

This position will report to the Head of Global Market Access and will lead and coordinate the development of value, market access, and pricing strategies with the goal of achieving optimal access for Ionis’ pipeline products. The position is expected to start in January 2027. 

WORK LOCATION:  This role may be based in one of the following arrangements: 

  • In-office at Ionis headquarters in Carlsbad, California (Hybrid Optional) 
  • In-office in Boston, Massachusetts (Hybrid Optional) 
  • Remote, with travel of up to 15% of working days 

      RESPONSIBILITIES: 

      The Director, Global Market Access will:  

      • Lead the development of asset-specific global market access strategies, leveraging personal knowledge and payer insights, to ensure robust and validated pricing and reimbursement assumptions
      • Drive integration of payer requirements and preferences into clinical and evidence generation plans, partnering with cross-functional colleagues to optimize development programs
      • Assess the pricing and reimbursement potential in the US across all channels and other key global markets to support business needs and identify opportunities for value demonstration
      • Lead scientific advice consultations to ensure design and endpoints provide required evidence for payer and HTA submissions
      • Generate payer value propositions, global value dossiers, JCA submissions, objection handlers, and global pricing policies
      • Collaborate with functions such as Commercial, Medical Affairs, HEOR, Clinical Development, Portfolio Planning, Market Insights, and Regulatory to ensure understanding of global payer markets and emerging pricing and access evolutions and to drive new processes
      • Manage external partners and vendors to conduct market research on the access landscape, payer unmet needs, current standard of care, value proposition, pricing, and access
      • Serve as a strategic pricing and market access advisor to Business Development for in-license and out-licensing opportunities

      REQUIREMENTS:  

      • Education: Undergraduate bachelor’s degree required, preferred in science with at least 15 years of experience in Pricing and Market Access OR science-based post-graduate degree or MBA with at least 12 years of experience in Pricing and Market Access
      • Expertise: Deep knowledge of global market access landscapes, including drivers of payer decision making, HTAs, pricing, contracting and tendering, relevance and importance of HEOR evidence, policies and regulations, etc. and differences by markets
      • Experience: Experience in developing market access strategies, pricing and access assumptions, and payer value propositions, and in informing development programs to optimize access in the US and other key global markets
      • Strategic: Knowledgeable about key healthcare and payer policies and proactive in adapting to evolving policies, processes, competitive landscapes, and data and able to integrate perspectives from different stakeholders
      • Communication: Exceptional verbal and written communication skills, with the ability to convey complex concepts clearly and persuasively, tailored to relevant audiences
      • Collaboration and interpersonal skills: Strong leadership and communication skills that can foster positive engagement with cross-functional partners and influence decision making
      • Bias to action: Innate curiosity to learn, with strong personal drive, self-starter initiative, and results-oriented spirit to drive to recommendations and creative solutions
      • Agility: Experience in managing and leading multiple projects across different programs and therapeutic areas

        

       

      Please visit our website, http://www.ionis.com for more information about Ionis and to apply for this position; reference requisition #IONIS004120

      Ionis offers an excellent benefits package! Follow this link for more details: Ionis Benefits

      Full Benefits Link: https://ionis.com/careers#:~:text=Highly competitive benefits

      The pay scale for this position is $220,000 to $260,000

      NO PHONE CALLS PLEASE. PRINCIPALS ONLY.

      Ionis Pharmaceuticals, Inc. and all its subsidiaries are proud to be EEO employers.

      Salary : $220,000 - $260,000

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