Supply Planning Manager

Job Title: Supply Planning Manager

Location: Boston, MA

Duration: 12 Months (Possible Extension)

Job Description:

The Manager, Supply Planning is embedded within Client's External Manufacturing organization. This individual will own the end-to-end supply planning function for Verve Therapeutics' clinical programs, operating in a fully outsourced CDMO model built on mRNA/LNP technology. The role is foundational to the team's S&OP process design and will serve as the primary driver of 18-month rolling MRP for clinical drug product supply.

KEY RESPONSIBILITIES:

Supply Planning & MRP:

• Develop and maintain rolling supply plans for clinical drug product
• Generate forward-looking material requirements for drug substance intermediates and critical excipients
• Manage supply plan assumptions, risk scenarios, and inventory coverage Clients in alignment with program timelines

S&OP Process Development:

• Build and maintain S&OP templates, KPIs, and reporting dashboards
• Prepare and present supply plan summaries for cross-functional leadership reviews

CDMO Network Coordination:

• Translate supply plans into manufacturing schedules coordinated across external CDMOs
• Monitor schedule adherence, batch release timelines, and supply risk through collaborative CDMO governance
• Maintain material genealogy and lot traceability across the multi-step supply chain

Risk & Inventory Management:

• Develop safety stock strategies for critical materials, accounting for CDMO lead times, shelf-life/expiry constraints, and clinical trial uncertainty
• Identify and escalate supply risks with mitigation options framed for leadership decision-making
• Support annual reportable change and regulatory change management (Client) from a supply continuity standpoint

QUALIFICATIONS:

Required:

• Bachelor's degree in Supply Chain, Engineering, Life Sciences, or related field; advanced degree a plus
• 5 years of supply chain or supply planning experience in pharmaceutical, biotech, or CDMO environment
• Hands-on experience with MRP/ERP systems (SAP strongly preferred)
• Direct experience with clinical supply planning in an outsourced manufacturing model
• Strong analytical skills; proficiency with supply planning tools and Excel/dashboard platforms

Preferred:

• Experience with advanced therapy or biologic modalities (LNP, mRNA, gene therapy, oligonucleoProduct)
• Familiarity with S&OP/IBP process design and implementation
• Exposure to Client regulatory requirements (IND-stage) and supply risk classification
• APICS CPIM or CSCP certification