Demo

Analytical Scientist

Integrated Resources, Inc ( IRI )
Cambridge, MA Contractor
POSTED ON 4/29/2026
AVAILABLE BEFORE 5/28/2026

Duration: 7 months


Responsibilities:

  • Develop, qualify, and troubleshoot chromatographic (GC, HPLC/UPLC) and LCMS based methods for the identification, characterization, and impurity profiling of oligonucleotides, siRNAs, and their formulations, as well as raw material related analytical methods and other methods as needed.
  • Understand and apply advanced scientific principles, theories, concepts, practices and standards to process and analytical development.
  • Provide analytical support for investigations leading by quality, manufacturing, supply chain.
  • Perform testing of late development siRNA candidates and their formulations for their characterization.
  • Author method development and qualification reports and SOPs for test methods. Evaluate suitability of new methods and oversee method qualification and validation in the external contract testing labs.
  • Author and review analytical sections in regulatory submission documents.
  • Apply strong technical knowledge of organic and analytical chemistry to support laboratory investigations (deviations/OOS/OOT), as needed.
  • May serve as a primary contact person for cross-departmental needs or projects and be accountable for key deliverables.
  • Contribute to the development and/or improvement of technical capabilities as well as initiatives to improve department efficiency.


Qualifications

  • PhD in Chemistry, Biochemistry or related disciplines with 0-4 years industry experience, Master’s degree with > 5 years related industry experience or Bachelor’s degree with > 8 years related industry experience respectively, with demonstrated chromatographic separation, method development / qualification and structure elucidation expertise.
  • Experience with HPLC/UPLC and LCMS-based analytical method development desired.
  • Hands-on experience with oligonucleotides, proteins, or peptides is a plus.
  • Familiarity with instrument troubleshooting and software including Empower, MassHunter, and UNIFI preferred.
  • Knowledge of GxP requirements and application of statistical methods in the analytical laboratory is a plus.
  • Strong interpersonal skills, communication, and collaboration.

Salary : $40 - $46

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