Senior Clinical Research Coordinator

Company Description The Institute for Neurodegenerative Disorders (IND) is an independent 501(c)(3) nonprofit research institute based in New Haven, Connecticut, founded in 2001. IND’s multidisciplinary team includes neurologists, nurses, study coordinators, neuropsychologists, and nuclear medicine technologists collaborating to advance clinical research. The organization is dedicated to developing diagnostic tools and new treatments for patients with neurodegenerative conditions. IND envisions a future where research enables early detection, effective treatment, and prevention of neurologic diseases, with clinical research at the core of this mission. Candidates will join a purpose-driven environment focused on meaningful impact for patients and families.

Role Description: The Senior Clinical Research Coordinator (Sr. CRC) serves in a lead role in the conduct of complex clinical research studies and functions as a subject matter expert within the clinic. Responsibilities include oversight of complex protocols, participant management, regulatory compliance, sponsor interactions, mentorship of junior staff, and support of operational initiatives. The Sr. CRC collaborates with multidisciplinary teams to support high-quality study conduct, participant experience, and continuous improvement efforts while participating in cross-training and providing cross-coverage support as needed, consistent with training, competency, and clinic needs.

Responsibilities

• Lead and independently manage complex clinical research studies, serving as primary coordinator and key contact for assigned studies while ensuring protocol adherence, regulatory compliance, participant safety, and high-quality study execution.
• Conduct and oversee complex participant visits, including screening activities, informed consent processes, neuropsychological assessments, phlebotomy, biological specimen management, collection of protocol-required clinical data, participant follow-up, and procedural support consistent with training and delegated responsibilities.
• Serve as a primary point of contact for sponsors, monitors, investigators, and multidisciplinary teams, supporting study start-up activities, monitoring visits, audits, inspections, and ongoing study execution.
• Identify, manage, and escalate protocol deviations, participant safety concerns, adverse events, and noncompliance issues, collaborate with regulatory and clinic leadership to support resolution and minimize operational risk.
• Support study planning, operational workflow optimization, and resource coordination, contributing to continuous improvement initiatives and efficient study execution across protocols.
• Provide mentorship, training, and operational guidance to CRC I, CRC II, and study support team, reinforcing Good Clinical Practice (GCP), protocol adherence, and development of clinical research competencies.
• Support recruitment strategy development, participant retention efforts, and enrollment tracking, contributing to achievement of study goals and participant experience initiatives.
• Participate in cross-training and provide cross-coverage support as needed for clinical and operational activities outside primary study coordination responsibilities, consistent with training, competency, and clinic needs.
• Collaborate effectively across multidisciplinary teams and contribute expertise to clinic initiatives, while performing additional duties assigned by supervisor or clinic leadership

Required Skills and Qualifications

• Bachelor’s degree in science, healthcare, psychology, public health, nursing, or related field OR equivalent combination of education and relevant healthcare, clinical, or research experience.
• Typical experience: 5–8 years of clinical research, healthcare, or equivalent experience with demonstrated progression managing increasingly complex studies.
• Advanced understanding of Good Clinical Practice (GCP), Good Documentation Practice (GDP), human subject research principles, clinical research regulatory requirements, and protocol implementation.
• Demonstrated ability to independently manage complex studies, mentor staff, navigate sensitive participant situations, maintain professionalism and confidentiality, and collaborate effectively across multidisciplinary teams.
• Strong organizational, communication, leadership, critical thinking, and problem-solving skills with the ability to manage competing priorities while supporting operational effectiveness and regulatory compliance.
• Advanced working knowledge of medical terminology, electronic documentation systems, and clinical research technology platforms.
• Demonstrated commitment to professionalism, ethical conduct, participant safety, confidentiality, accountability, and continuous improvement.
• Experience and/or certification in phlebotomy.
• Basic Life Support (BLS) certification.

Preferred Qualifications

• Previous experience independently coordinating complex clinical research studies within clinical research, healthcare, academic, pharmaceutical, biotech, or site-based research settings.
• Experience with neurology, neurodegenerative disease, imaging research, monitoring visits, audits, sponsor interactions, regulatory activities, protocol implementation, and operational workflow optimization.
• Experience mentoring, training, or supporting development of research staff.
• Experience using electronic data capture systems (EDC/eCRF), CTMS, research databases, and other clinical research technology platforms.
• Clinical research certification (CCRP, CCRC, or equivalent) preferred.

Physical and Work Environment Requirements

• Exposure to ionizing radiation in accordance with study protocols and safety requirements.
• Exposure to biohazardous materials and bodily fluids, including blood, urine, cerebrospinal fluid (CSF), and other protocol-required biological specimens.
• Ability to stand, walk, bend, reach, and perform repetitive tasks associated with participant visits and study Ability to lift, move, or position up to 50 pounds, including study equipment and materials, with or without reasonable accommodation.
• Ability to move between clinic locations, imaging facilities, and other approved sites as needed to support participant visits, study activities, and operational needs, in accordance with institutional policies and safety requirements.
• Intermittent evening and weekend work may be required to support study activities.

Beyond the Job

At IND, we believe that when our people are supported, they can do their best work. We’re committed to taking care of our team so they can focus on the important work of advancing research. In addition to joining a mission-driven, innovative team with a collaborative and inclusive culture, you will also enjoy:

• Competitive base salary: $74k - $88k $ (D.O.E.)

• Bonus eligible

• Medical, dental, and vision Insurance

• Flexible Spending Accounts (FSA)

• Employer-paid life and disability insurance

• Paid time off: Flexible vacation, sick and holidays

• Contribution to retirement plan (403b)

• Professional development opportunities

• Professional liability insurance

• CME and professional organization membership support

IND is an equal opportunity employer. We encourage applications from individuals who will help us build and sustain a diverse, equitable, and inclusive workplace. Diversity may include, but is not limited to, race, religion, ethnicity, sex, gender identity, sexual orientation, socioeconomic background, geographic origin, ability and disability, political beliefs, and age. We value the unique perspectives and experience each team member brings to advancing our mission.