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Protein Engineering Scientist

Impact Solutions
Cambridge, MA Full Time
POSTED ON 4/2/2023 CLOSED ON 9/30/2023

What are the responsibilities and job description for the Protein Engineering Scientist position at Impact Solutions?

We have been engaged to find a Protein Engineering Scientist with hands-on experience in antibody/protein design and lab development with a focus on Yeast Surface Display projects. The position will work closely with experienced scientists in a dynamic, fast-paced and highly collaborative environment.

In this role, you will play a key role in design and implementation of Yeast Surface Display campaigns (YSD) for engineering of affinity, developability, epitope mapping etc. You will also represent the Department in cross-functional project teams. Previous experiences with YSD technology highly desired. Previous experience with multi specific-antigen interaction is a plus.

*Exciting career opportunity with a global leader in the Life Sciences, don’t wait apply today!

Protein Engineering Scientist overview :

  • YSD technology for various antibody engineering efforts. Including, but not limited to, affinity tuning, pH-dependent protein-protein interactions, liability/developability engineering and fast epitope mapping.
  • Develop and optimize assays to screen the engineered biotherapeutics for improved biological properties, binding affinity and biophysical characteristics.
  • Documenting and presenting experimental results, conclusions and interpretations at departmental and cross-functional project team meetings.
  • Write scientific publications and present at conferences.
  • Contribute to patent applications.

Protein Engineering Scientist include :

  • Ph.D. in biologic sciences, molecular cell biology, protein engineering, or similar, with 0-3 years of research experience in academia and/or Biotech or Pharma environment.
  • Self-motivated and highly collaborative to work in a cross-cultural, multidisciplinary, team-oriented environment with excellent communication and organization skills.
  • Expertise in strategizing, designing and performing Yeast Surface Display (YSD) campaigns.
  • Well-versed in protein engineering technologies and principles, including protein structure-function relationships, biophysical and biochemical analysis.
  • Proven experience in antibody protein design is desired.
  • Familiarity in a wide range of screening assays and analytical methods, such as ELISA, ALPHA Screen, Octet, Biacore, HPLC, DSC/DSF, MALS.
  • Experience with high-throughput analytical methods is a plus.
  • Track record of scientific accomplishments as evidenced by a strong publication record.
  • People management experience preferred, but not required.

Industry: Protein Engineering Scientist, Yeast Surface Display, Antibody, Protein

Job Code: j-1519

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