What are the responsibilities and job description for the Director, Safety Science position at IDEAYA Biosciences?
Non-Solicitation Policy And Notice To Agencies And Recruiters
IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships. Submission of unsolicited candidate resumes by agencies or recruiters with or without a contract in place with IDEAYA Biosciences Inc. will not create any implied obligation. Failure to comply with this policy will result in disqualification from current and future business opportunities with IDEAYA Biosciences. All recruiting and talent agency decisions are strictly managed by the internal IDEAYA Human Resources function. All communication by external agencies and recruiters must be directed to humanresources@ideayabio.com. We ask that you only email your interest once.
Job Summary
About IDEAYA Biosciences:
IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.
When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see www.ideayabio.com.
Location: South San Francisco or San Diego, CA.
Position Summary
We are seeking a Director of Safety Science to join the IDEAYA team. This position will be reporting to the Vice President of Drug Safety. This role leads safety monitoring for investigational and marketed products, ensuring compliance with corporate strategies and regulatory standards. Responsibilities include managing safety deliverables (e.g., governance, signal detection, reporting), supervising safety scientists, and conducting safety analyses.The position oversees Risk Management Plans (RMPs), Risk Evaluation and Mitigation Strategies (REMS), and the preparation of regulatory safety documents (e.g., PBRERs, DSURs, NDAs). It involves cross-functional collaboration on signal detection, risk management, and benefit-risk assessments, while maintaining expertise in drug safety and regulatory trends. Additional duties include vendor oversight, process improvements, and participation in audits and inspections.
This position is based in our South San Francisco or San Diego offices and required to be onsite four days per week per our company policy.
Job Description
What you’ll do:
Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs.
The expected salary range for the role of Director, Safety Science, is $235,000-$290,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process.
The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.
IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.
IDEAYA's Non-Solicitation Policy strictly prohibits agencies and recruiters from any contact and communication with IDEAYA employees, managers, and leaders to submit unsolicited candidate resumes and/or to solicit business partnerships. Submission of unsolicited candidate resumes by agencies or recruiters with or without a contract in place with IDEAYA Biosciences Inc. will not create any implied obligation. Failure to comply with this policy will result in disqualification from current and future business opportunities with IDEAYA Biosciences. All recruiting and talent agency decisions are strictly managed by the internal IDEAYA Human Resources function. All communication by external agencies and recruiters must be directed to humanresources@ideayabio.com. We ask that you only email your interest once.
Job Summary
About IDEAYA Biosciences:
IDEAYA is a precision medicine oncology company committed to the discovery, development, and commercialization of transformative therapies for cancer. Our approach integrates expertise in small-molecule drug discovery, structural biology and bioinformatics with robust internal capabilities in identifying and validating translational biomarkers to develop tailored, potentially first-in-class targeted therapies aligned to the genetic drivers of disease. We have built a deep pipeline of product candidates focused on synthetic lethality and antibody-drug conjugates, or ADCs, for molecularly defined solid tumor indications. Our mission is to bring forth the next wave of precision oncology therapies that are more selective, more effective, and deeply personalized with the goal of altering the course of disease and improving clinical outcomes for patients with cancer.
When you're at IDEAYA, you will be in the midst of brilliant minds working on precision medicine therapies to help cancer patients. We are passionate and committed about being on the forefront of oncology medicine, which means we all have a high internal drive that is at the very core of every person at IDEAYA. We are inquisitive, ask deep questions, and are data-driven innovators who like to collaborate and use team work to move science forward. For more information, please see www.ideayabio.com.
Location: South San Francisco or San Diego, CA.
Position Summary
We are seeking a Director of Safety Science to join the IDEAYA team. This position will be reporting to the Vice President of Drug Safety. This role leads safety monitoring for investigational and marketed products, ensuring compliance with corporate strategies and regulatory standards. Responsibilities include managing safety deliverables (e.g., governance, signal detection, reporting), supervising safety scientists, and conducting safety analyses.The position oversees Risk Management Plans (RMPs), Risk Evaluation and Mitigation Strategies (REMS), and the preparation of regulatory safety documents (e.g., PBRERs, DSURs, NDAs). It involves cross-functional collaboration on signal detection, risk management, and benefit-risk assessments, while maintaining expertise in drug safety and regulatory trends. Additional duties include vendor oversight, process improvements, and participation in audits and inspections.
This position is based in our South San Francisco or San Diego offices and required to be onsite four days per week per our company policy.
Job Description
What you’ll do:
- Report directly to the Vice President of Drug Safety and indirectly to the Senior Medical Director of Drug Safety.
- Lead safety monitoring for investigational and marketed products, ensuring alignment with corporate development strategies.
- Oversee core safety deliverables, including safety governance, signal detection/management, periodic/aggregate reporting, and case processing.
- Supervise and mentor all safety scientists, fostering a collaborative and high-performing team.
- Conduct safety analyses using case series, data summaries, adverse event trends, and clinical/post-marketing data.
- Review medical and scientific literature for signal detection and aggregate reporting.
- Develop and maintain product-specific Risk Management Plans (RMPs) and Risk Evaluation and Mitigation Strategies (REMS).
- Perform safety data monitoring, interpretation, and analysis.
- Lead the preparation of safety deliverables, including integrated safety reports and regulatory documents (e.g., PBRER/PSUR, DSUR, PADERs).
- Provide safety input to clinical documents such as Investigator’s Brochures, study protocols, and clinical study reports.
- Ensure consistency in safety and risk management content across regulatory submissions.
- Partner with safety physicians and cross-functional teams on signal detection and risk management activities.
- Participate in safety governance meetings and contribute to benefit-risk assessments.
- Author and review safety sections for regulatory packages, including NDAs and responses to health authority queries.
- Support pharmacovigilance vendor oversight, process improvement initiatives, and inspections/audits.
- Maintain up-to-date expertise in disease areas, drug safety, regulatory trends, and business practices.
- PharmD, RN, or MD required; advanced degrees (e.g., Master’s) preferred.
- At least 6 years of experience in patient safety and pharmacovigilance, including team management.
- More than 3 years of experience authoring and reviewing periodic/ad hoc safety reports and clinical documents (e.g., PSURs, DSURs, Clinical Overviews).
- Expertise in safety analyses, signal detection, risk management, and health authority responses.
- Experience with NDA/MAA filings.
- Strong ability to interpret and integrate safety data.
- Effective communication skills (written and verbal) for internal and external audiences.
- Proven leadership in mentoring and managing scientific teams.
- Must be authorized to work in the United States on a full-time basis.
Along with our inspiring mission, and highly collaborative and inclusive environment, IDEAYA offers a competitive total rewards package that reflects our pay-for-performance philosophy where employees are eligible to be considered for merit-based salary increases, company discretionary short-term incentive plan participation, and company discretionary stock option awards (based on board approval). Our comprehensive benefits package includes, but is not limited to, medical/dental/vision coverage (100% company paid for employees and 90% company paid for dependents), 401k, ESPP, and wellness programs.
The expected salary range for the role of Director, Safety Science, is $235,000-$290,000. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the office location where this open position is located, the final candidates’ experience within their profession, experience in the disease areas we are striving to make an impact in as a company, length of time within the industry, educational background, and performance during the interview process.
The Company complies with all laws respecting equal employment opportunities and does not discriminate against applicants with regard to any protected characteristic as defined by federal, state, and local law. This position requires you to work onsite in the office at the Company’s facilities for training & meetings, with work-from-home flexibility, and the Company requires that all employees working in its facilities be fully vaccinated (except as required by applicable law). Therefore, this position requires you to be fully vaccinated from COVID-19, subject to reasonable accommodations for medical or religious reasons, and/or as otherwise required by applicable law. The Company considers you fully vaccinated once 14 days have passed since you received either the second dose in a two-dose COVID-19 vaccine series or a single-dose COVID-19 vaccine. The vaccine must have been FDA approved, have emergency use authorization from the FDA, or, for persons fully vaccinated outside of the U.S., be listed for emergency use by the World Health Organization.
IDEAYA is an equal opportunity employer. In accordance with applicable law, IDEAYA does not discriminate in hiring or otherwise in employment based on race, color, religion, sex, national origin, age, marital or veteran status, disability, sexual orientation, or any other legally protected status. EOE/AA/Vets.
Salary : $235,000 - $290,000
