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Senior Staff Scientist

ICON plc
Wilmington, DE Full Time
POSTED ON 12/11/2025 CLOSED ON 2/11/2026

What are the responsibilities and job description for the Senior Staff Scientist position at ICON plc?

Senior Staff Scientist - Immunology
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development
Join our innovative preclinical research team and play a pivotal role in advancing novel therapies for inflammatory and dermatological diseases. As a Staff or Senior Staff Scientist, you will directly influence early-stage drug discovery programs, generating insights that shape treatments and improve patients’ lives. This position offers an exciting opportunity to combine scientific rigor with creativity in a collaborative, fast-paced environment.
What You Will Be Doing:
  • Design and execute biologically relevant assays to elucidate disease mechanisms and accelerate therapeutic discovery.
  • Analyze and interpret complex datasets to guide strategic decisions in discovery programs.
  • Perform advanced cellular and molecular biology assays using cutting-edge technologies.
  • Maintain accurate, detailed records of experimental procedures and results to ensure reproducibility and compliance.
  • Communicate findings effectively to cross-functional teams and leadership, influencing program direction.
  • Collaborate within a high-performing team while developing as an independent scientific contributor.
Your Profile:
  • Doctorate (Ph.D.) in Immunology, Biochemistry, Molecular Biology, Cell Biology, or related discipline.
  • Strong background in immunology or related biological sciences.
  • Proficiency in molecular and cellular techniques, including RT-PCR, Western blotting, ELISA, and sterile cell culture.
  • Proficiency in multi-color flow cytometry.
  • Excellent organizational skills with the ability to manage multiple priorities.
  • Outstanding written and verbal communication skills.
  • Demonstrated ability to work independently and collaboratively in a team environment.
  • Commitment to scientific rigor and delivering impactful research.
  • 1-2 years’ experience in pharma industry or post-doctoral experience.
  • Experience with in-vivo disease models (rodents).
  • Familiarity with human immunology (innate and adaptive) and/or prior industry experience.
  • Hands-on experience with multiplex protein or RNA-based technologies.
  • Enthusiasm for fostering a culture of scientific curiosity and open collaboration.
What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs.
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
  • Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being.
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.
Visit our
careers site
to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Salary.com Estimation for Senior Staff Scientist in Wilmington, DE
$96,943 to $118,941
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