Demo

Principal R Programmer

ICON Plc
Blue, PA Full Time
POSTED ON 4/24/2026
AVAILABLE BEFORE 5/23/2026
Principal R Programmer-Remote
ICON plc is a world-leading healthcare intelligence and clinical research organization. We’re proud to foster an inclusive environment driving innovation and excellence, and we welcome you to join us on our mission to shape the future of clinical development
We are currently seeking a Principal R Programmer to join our diverse and dynamic team. As a Principal R Programmer at ICON, you will play a vital role in the analysis and reporting of clinical trial data, ensuring the integrity and accuracy of statistical outputs. You will contribute to the advancement of our clinical studies by developing and validating complex statistical programs, collaborating closely with biostatisticians, and adhering to regulatory standards.
What You Will Be Doing:
  • Designing, developing, and validating R programs for statistical analysis and reporting of clinical trial data.
  • Working closely with biostatisticians to create comprehensive analysis plans and apply appropriate statistical methods.
  • Performing quality control checks and reviewing statistical outputs to ensure compliance with project specifications and regulatory guidelines.
  • Assisting in the preparation of statistical reports, presentations, and regulatory submissions to support clinical development programs.
  • Mentoring junior programmers and contributing to team development by sharing best practices and technical knowledge.
Your Profile:
  • Bachelor’s or Master’s degree in Statistics, Mathematics, Computer Science, or a related field.
  • Significant experience in PK/PD statistical programming within the clinical research or pharmaceutical industry, using R.
  • Strong proficiency in R programming and a solid understanding of statistical concepts and methodologies.
  • Excellent analytical skills, attention to detail, and the ability to manage multiple projects simultaneously.
  • Strong communication and interpersonal skills, with the ability to work collaboratively within a multidisciplinary team.
  • Must have advanced R programming skills, including tidyverse, ggplot2, Markdown, Quarto, Shiny, etc. Python and/or SAS programming skills are a plus, but not required.
  • Knowledge of CDISC standards (SEND, SDTM, and ADaM) is required.
  • PK/PD knowledge and experience of PK/PD concepts and related programming is required.
  • Experience visualizing/presenting data for internal stakeholders or clients
  • Capable of implementing more advanced modeling and statistical procedures as requested by study.
What ICON can offer you:
Our success depends on the quality of our people. That’s why we’ve made it a priority to build a diverse culture that rewards high performance and nurtures talent.
In addition to your competitive salary, ICON offers a range of additional benefits. Our benefits are designed to be competitive within each country and are focused on well-being and work life balance opportunities for you and your family.
Our benefits examples include:
  • Various annual leave entitlements
  • A range of health insurance offerings to suit you and your family’s needs.
  • Competitive retirement planning offerings to maximize savings and plan with confidence for the years ahead.
  • Global Employee Assistance Programme, TELUS Health, offering 24-hour access to a global network of over 80,000 independent specialised professionals who are there to support you and your family’s well-being.
  • Life assurance
  • Flexible country-specific optional benefits, including childcare vouchers, bike purchase schemes, discounted gym memberships, subsidised travel passes, health assessments, among others.
Visit our
careers site
to read more about the benefits ICON offers.
At ICON, inclusion & belonging are fundamental to our culture and values. We’re dedicated to providing an inclusive and accessible environment for all candidates. ICON is committed to providing a workplace free of discrimination and harassment. All qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.
If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please let us know
Interested in the role, but unsure if you meet all of the requirements? We would encourage you to apply regardless – there’s every chance you’re exactly what we’re looking for here at ICON whether it is for this or other roles.

Salary.com Estimation for Principal R Programmer in Blue, PA
$124,400 to $148,053
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