Demo

Sr. Systems Engineer

Hologic Careers
Newark, DE Full Time
POSTED ON 10/8/2026
AVAILABLE BEFORE 12/6/2026

Position Summary
The Lead Systems Engineer is responsible for owning and driving the system-level definition, integration, and verification of capital/hardware equipment. This role provides technical leadership across disciplines (hardware, software, firmware, mechanical, quality, manufacturing), ensures that system requirements are well-defined and traceable, and leads the team to deliver compliant, robust, and customer-focused solutions throughout the product lifecycle. 

 

Key Responsibilities

  • System Definition & Architecture
    • Lead the definition of system requirements, use cases, and interfaces based on customer, business, and regulatory needs.
    • Develop and maintain system architecture, subsystem breakdown, and control documents.
    • Ensure proper requirements flow-down and traceability from system to subsystems and components.
  • Technical Leadership
    • Serve as the primary technical point of contact for system-level topics across cross-functional teams.
    • Provide technical support and guidance to cross-functional teams to ensure alignment with system architecture and requirements.
    • Lead technical reviews (requirements, design, integration, verification) and drive closure of actions and risks.
  • Integration & Verification
    • Plan and lead system integration activities, including test strategy, test plans, and test execution at system level.
    • Coordinate and perform system verification and validation to ensure compliance requirements and fitness for use.
    • Analyze test results, lead troubleshooting, and drive root cause investigations and corrective actions.
  • Lifecycle & Risk Management
    • Support product sustainability, including change impact assessments.
    • Identify, track, and mitigate technical risks; support FMEA and other risk management activities.
    • Collaborate with cross-functional team to ensure design compliance, reliability, and sustainability.
  • Stakeholder & Project Support
    • Collaborate with product management and marketing to translate customer needs into system capabilities.
    • Contribute to project planning, effort estimation, milestones, and system-level deliverables.
    • Support regulatory submissions, audits, and customer interactions as the system technical owner.
  • Mentoring & Continuous Improvement
    • Mentor junior systems and design engineers; promote best practices in systems engineering.
    • Champion continuous improvement of requirements management, architecture, and verification processes and tools.

Required Qualifications

  • Bachelor’s degree in Systems Engineering, Electrical Engineering, Mechanical Engineering, Software Engineering, or related field.
  • 5 years of experience in systems engineering or equivalent multi-disciplinary engineering role.
  • Proven experience leading complex, cross-functional technical projects or products.
  • Hands-on experience with requirements management, system architecture, and system integration/verification.

Preferred Qualifications

  • Master’s degree in Systems Engineering or related discipline.
  • Experience in a regulated industry (e.g., medical devices, aerospace, automotive, industrial).
  • Familiarity with systems engineering standards and practices (e.g., INCOSE, V-model, MBSE, SysML, etc.).
  • Experience with requirements management tools (e.g., DOORS, Jama, Polarion, etc.).

Key Skills and Competencies

  • Strong system-level thinking and ability to understand interactions across hardware, software, and mechanical components.
  • Excellent analytical, problem-solving, and troubleshooting skills.
  • Strong leadership, influence, and communication skills across all organizational levels.
  • Ability to drive alignment, make trade-off decisions, and manage ambiguity.
  • Organized, detail-oriented, and able to manage multiple priorities in parallel.

So why join Hologic?

We are committed to making Hologic the company where top talent comes to grow. For you to succeed, we want to enable you with the tools and knowledge required and so we provide comprehensive training when you join as well as continued development and training throughout your career. We offer a competitive salary and an annual bonus scheme, one of our talent partners can discuss this in more detail with you.

If you have the right skills and experience and want to join our team, apply today. We can’t wait to hear from you!

The annualized base salary range for this role is $97,600 - $152,700 and is bonus eligible. Final compensation packages will ultimately depend on factors including relevant experience, skillset, knowledge, geography, education, business needs and market demand.

Agency and Third-Party Recruiter Notice: Agencies that submit a resume to Hologic must have a current executed Hologic Agency Agreement executed by a member of the Human Resource Department. In addition Agencies may only submit candidates to positions for which they have been invited to do so by a Hologic Recruiter. All resumes must be sent to the Hologic Recruiter under these terms or they will not be considered.

Hologic, Inc. is proud to be an Equal Opportunity Employer inclusive of disability and veterans.

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