Demo

Senior Metrology Specialist

Guardant Health
Redwood, CA Full Time
POSTED ON 8/1/2026
AVAILABLE BEFORE 9/7/2026
Company Description

Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant® is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visit guardanthealth.com and follow the company on LinkedIn, X (Twitter) and Facebook.

Within the Automation Service Engineering organization, the Senior Metrology Specialist is part of a dynamic team that supports all of the Guardant Health sites across California (Redwood City, Palo Alto, Union City and San Diego), and is responsible for the oversight, installation/qualification, calibration, maintenance, and repair of analytical and microbiology equipment. In this role, the candidate will help lead metrology strategies, advanced technical operations, and reliability initiatives to ensure measurement accuracy, regulatory compliance, and optimal asset performance across the organization.

The Senior Metrology Specialist is a subject matter expert (SME) responsible for complex calibrations, system optimization, and leadership of the metrology program. This role drives innovation, standardization, and continuous improvement while mentoring staff and influencing cross-functional decisions.

Responsibilities

  • Serve as an SME for metrology systems, calibration strategies, and measurement technologies.
  • Perform and oversee complex calibrations, repairs, and equipment qualifications (IQ/OQ).
  • Lead development and validation of advanced calibration methods and measurement system analysis.
  • Analyze calibration and reliability data to identify trends, risks, and optimization opportunities.
  • Design and implement reliability and proactive strategies to ensure equipment robustness (predictive maintenance, condition monitoring).
  • Own and optimize CMMS/EAM systems, including asset strategies, KPIs, and reporting (e.g., MTBF, MTTR).
  • Lead root cause investigations and implement robust corrective/preventive actions.
  • Drive standardization of SOPs, work instructions, and engineering documentation.
  • Act as technical lead during audits and regulatory inspections (e.g., ISO/IEC 17025, GMP, CAP, FDA).
  • Manage vendor relationships, service contracts, and outsourced calibration programs.
  • Lead the team in ownership and management of the temperature monitoring system.
  • Lead capital projects including equipment selection, validation, and lifecycle planning.
  • Provide mentorship, technical training, and career development for metrology staff.
  • Collaborate with Automation Service Engineering, Quality, R&D, Manufacturing, and Facilities to align metrology with business objectives.
  • Identify and implement cost-saving initiatives and process improvements.
  • Understand and adhere to internal and external regulations, procedures & policies
  • Perform other duties as assigned.

Qualifications

  • Bachelor’s degree in Metrology, Engineering, or related field (advanced degree preferred), or equivalent experience.
  • 5 years of relevant experience.
  • Deep expertise in metrology principles, uncertainty analysis, and calibration systems.
  • Advanced knowledge of ISO/IEC 17025, GMP, and regulatory compliance frameworks.
  • Strong experience in reliability engineering and asset lifecycle management.
  • Proficiency with CMMS/EAM systems and data analytics tools.
  • Working knowledge of Viewpoint or similar environmental monitoring systems.
  • Basic troubleshooting skills related to cold storage and other laboratory equipment.
  • Demonstrated leadership, mentoring, and project management experience.
  • Excellent analytical, problem-solving, and communication skills.
  • Experience applying 5S, Lean Manufacturing methodologies.
  • Ability to influence cross-functional stakeholders and drive strategic initiatives.
  • Ability to take part in an on-call rotation with afterhours/weekend response as needed.
  • Willingness to travel up to 30% as needed.

AI & Digital Fluency

  • Demonstrate curiosity, sound judgment, and the ability to critically evaluate and responsibly leverage AI-enabled tools in accordance with company policies, ethical standards, and regulatory requirements to improve the efficiency, effectiveness, and quality of work.

Hybrid Work Model: This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person/onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.

The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need. Primary Location: Redwood City, CA Primary Location Base Pay Range: $51 - $71 Other US Location(s) Base Pay Range: $44 - $60 If the role is performed in Colorado, the pay range for this job is: $46 - $64

Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk/office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.

Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com

A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).

Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

All your information will be kept confidential according to EEO guidelines.

To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our Privacy Notice for Job Applicants.

Please visit our career page at: http://www.guardanthealth.com/jobs/

Salary : $44 - $60

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